지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.9
- 수록면
- 131 - 137 (7page)
이용수
이 논문의 연구 히스토리 (7)
2014
Breast tumor mass in the metastatic mouse model injected with human MCF-7 cells was suppressed by engineered stem cells expressing therapeutic genes via apoptotic signaling pathway
Bo-Rim Yi
,
Kyung-Chul Choi
한국실험동물학회 학술발표대회 논문집
2014.08
학술대회자료
Carboxyl esterase in the tumor-tropic stem cells resulted in the suppression of tumor growth in a xenografted mouse model with primary and metastatic lung cancers
Bo-Rim Yi
,
Kyung-Chul Choi
한국실험동물학회 학술발표대회 논문집
2014.08
학술대회자료
2013
Development and application of neural stem cells for treating various human neurological diseases in animal models
Bo-Rim Yi
,
Seung U. Kim
,
Kyung-Chul Choi
Laboratory Animal Research
2013.09
학술저널
Chemo- and immune-therapies using engineered stem cells via upregulation of type I interferon alpha/beta receptor and BAX genes in a ductal breast cancer mouse model
Bo-Rim Yi
,
Seung U. Kim
,
Kyung-Chul Choi
한국실험동물학회 학술발표대회 논문집
2013.08
학술대회자료
Engineered stem cells, HB1.F3.CD and HB1.F3.CD.IFN-b cells, induced therapeutic effect on the primary and metastatic breast cancers in a xenograft mouse model
Bo-Rim Yi
,
Kyung-Chul Choi
한국실험동물학회 학술발표대회 논문집
2013.08
학술대회자료
2012
Therapeutic stem cells with cytosine deaminase and interferon-beta showed the antitumor effect via tumor-tropism in a xenograft mouse model implanted with endometrial cancer cells
Bo-Rim Yi
,
Seung U. Kim
,
Kyung-Chul Choi
한국실험동물학회 학술발표대회 논문집
2012.08
학술대회자료
Expression of bacterial cytosine deaminase and human interferon-beta in the stem cells resulted in the growth inhibition of pancreatic cancer cells in cellular and xenograft mouse model
Bo-Rim Yi
,
Doo-Jin Kim
,
Hye-Sun Kim
외 3명
한국실험동물학회 학술발표대회 논문집
2012.08
학술대회자료
- 이 논문의 후속연구가 궁금하신가요?
- 연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
- 이 논문의 연구 히스토리 확인하기
초록· 키워드
오류제보하기
Stem cells derived from adult tissues or the inner cell mass (ICM) of embryos in the mammalian blastocyst (BL) stage are capable of self-renewal and have remarkable potential for undergoing lineagespecific differentiation under in vitro culturing conditions. In particular, neural stem cells (NSCs) that selfrenew and differentiate into major cell types of the brain exist in the developing and adult central nervous system (CNS). The exact function and distribution of NSCs has been assessed, and they represent an interesting population that includes astrocytes, oligodendrocytes, and neurons. Many researchers have demonstrated functional recovery in animal models of various neurological diseases such as stroke, Parkinson’s disease (PD), brain tumors, and metastatic tumors. The safety and efficacy of stem cell-based therapies (SCTs) are also being evaluated in humans. The therapeutic efficacy of NSCs has been shown in the brain disorder-induced animal models, and animal models may be well established to perform the test before clinical stage. Taken together, data from the literature have indicated that therapeutic NSCs may be useful for selectively treating diverse types of human brain diseases without incurring adverse effects.
목차
NSC-based therapies for treating stroke in animal models
NSC-based therapies for treating PD in animal models
NSC-based therapies for treating brain tumor in animal models
NSC-based therapies for treating various human primary tumor in animal models
NSC-based therapies for treating metastatic tumor in animal models
Conclusion
References
참고문헌 (71)
참고문헌 신청
1. [학술지(정기간행물)] - Pauklin S / 2011 / Mouse pluripotent stem cells at a glance / J Cell Sci 124 (Pt 22) : 3727 ~ 3732
2. [학술지(정기간행물)] - Ogawa K / 2007 / Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells / J Cell Sci 120 (Pt 1) : 55 ~ 65
3. [학술지(정기간행물)] - Dado D / 2012 / Mechanical control of stem cell differentiation / Regen Med 7 (1) : 101 ~ 116
4. [학술지(정기간행물)] - Maul TM / 2011 / Mechanical stimuli differentially control stem cell behavior: morphology, proliferation, and differentiation / Biomech Model Mechanobiol 10 (6) : 939 ~ 953
5. [학술지(정기간행물)] - Ying QL / 2003 / Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture / Nat Biotechnol 21 (2) : 183 ~ 186
2. [학술지(정기간행물)] - Ogawa K / 2007 / Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells / J Cell Sci 120 (Pt 1) : 55 ~ 65
3. [학술지(정기간행물)] - Dado D / 2012 / Mechanical control of stem cell differentiation / Regen Med 7 (1) : 101 ~ 116
4. [학술지(정기간행물)] - Maul TM / 2011 / Mechanical stimuli differentially control stem cell behavior: morphology, proliferation, and differentiation / Biomech Model Mechanobiol 10 (6) : 939 ~ 953
5. [학술지(정기간행물)] - Ying QL / 2003 / Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture / Nat Biotechnol 21 (2) : 183 ~ 186
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UCI(KEPA) : I410-ECN-0101-2014-500-002858115