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논문 기본 정보

자료유형
학술저널
저자정보
임은채 (전남대학교) 신준재 (전남대학교) 박인택 (전남대학교) 한효경 (동국대학교) 김시욱 (조선대학교) 조훈 (조선대학교) 김성준 (전남대학교)
저널정보
한국생물공학회 KSBB Journal KSBB Journal 제25권 제6호
발행연도
2010.12
수록면
527 - 532 (6page)

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A thiazolidinedione derivative, TD49 with the highly selective algicide to red tide was newly synthesized and its acute toxicity was examined in order to evaluate the effect on aquatic ecosystems of coast. Major three species having important role in the food chain of marine ecosystem, such as Skeletonema costatum of microalgae, Daphnia magna of crustacea, Paralichthys olivaceus of flatfish fingerling were employed for the acute toxicity assessment. EC<SUB>50</SUB> or LC<SUB>50</SUB> as the assessment criterion was investigated to each specie, and NOEC (No Observed Effect Concentration) and PNEC (Predicted No Effect Concentration) from most sensitive specie to toxicity of TD49 were further calculated. EC<SUB>50</SUB> of S. costatum in 96-hour, EC<SUB>50</SUB> of D. magna in 48-hour, and LC<SUB>50</SUB> of P. olivaceus in 72-hour for TD49 were 0.34 μM, 0.68 μM, and 0.58 μM, respectively. NOEC from the results of S. costatum was estimated to be 0.20 μM and PNEC was estimated as 3.40 nM by applying factor value of 100 to EC50 0.34 μM of S. costatum. In addition, it was revealed that Solutol used as the dispersing agent of TD49 had very little toxic influence under the concentration range of 0~0.4 μM used in TD49 toxicity experiment. Although the estimated concentration of TD49 that will be sprayed onto the coastal field for the algicide is higher than NOEC value, it is considered that the spraying concentration would not be a considerable problem due to a dilution effect by tide at the opened coast.

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UCI(KEPA) : I410-ECN-0101-2014-400-002395729