지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.12
- 수록면
- 497 - 506 (10page)
이용수
초록· 키워드
오류제보하기
Vaccine is a protective clinical measure capable of persuading immune system against infectious agents. Vaccine can be categorized as live attenuated and inactivated. Live attenuated vaccines activate immunity similar to natural infection by replicating living organisms whereas inactivated vaccines are either whole cell vaccines, eliciting immune response by killed organisms,or subunit vaccines, stimulating immunity by non-replicating sub cellular parts. The components of vaccine play a critical role in deciding the immune response mediated by the vaccine. The innate immune responds against the antigen component. Adjuvants represent an importantcomponent of vaccine for enhancing the immunogenicity of the antigens. Subunit vaccines with isolated fractions of killed and recombinant antigens are mostly co-administered with adjuvants. The delivery system of the vaccine is another essential component to ensurethat vaccine is delivered to the right target with right dosage form. Furthermore, vaccine delivery system ensures that the desired immune response is achieved by manipulating the optimal interaction of vaccine and adjuvantwith the immune cell. The aforementioned components along with routes of administration of vaccine are the key elements of a successful vaccination procedure. Vaccines can be administered either orally or by parenteral routes. Many groups had made remarkable efforts for the development of new vaccine and delivery system. The emergence of new vaccine delivery system may lead to pursue the immunization goals with better clinical practices.
목차
Abstract
서론
백신의 효과 증대를 위한 백신보조제
생분해성 마이크로원형구조체 (Biodegradablemicrosphere)
백신의 효과향상을 위해 개발된 백신 전달 방법
REFERENCES
참고문헌 (68)
참고문헌 신청
1. [단행본] - Pier, G. B / 2004 / Immunology, Infection, and Immunity / ASM Press
2. [단행본] - Janeway, C. A. Jr / 2001 / Immunobiology / GarlandPublishing
3. [학술지(정기간행물)] - Kantoff, P. W / 2010 / Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer / N. Eng. J. of Med. 363 : 411 ~ 422
4. [학술지(정기간행물)] - Jennings, G. T / 2007 / Designing recombinant vaccines with viral properties: a rational approach to more effective vaccines / Curr. Mol. Med. 7 : 143 ~ 155
5. [학술지(정기간행물)] - Martin F. B / 2010 / Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns / Nat. Rev. Immunol. 10 : 787 ~ 796
2. [단행본] - Janeway, C. A. Jr / 2001 / Immunobiology / GarlandPublishing
3. [학술지(정기간행물)] - Kantoff, P. W / 2010 / Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer / N. Eng. J. of Med. 363 : 411 ~ 422
4. [학술지(정기간행물)] - Jennings, G. T / 2007 / Designing recombinant vaccines with viral properties: a rational approach to more effective vaccines / Curr. Mol. Med. 7 : 143 ~ 155
5. [학술지(정기간행물)] - Martin F. B / 2010 / Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns / Nat. Rev. Immunol. 10 : 787 ~ 796
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UCI(KEPA) : I410-ECN-0101-2014-400-002395683