지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.10
- 수록면
- 313 - 318 (6page)
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초록· 키워드
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Dimethyl sulfoxide (DMSO) increased the intracellular calcium ion concentration in stably transfected Drosophila melanogaster S2 cells expressing recombinant cyclooxygenase 1 (COX-1). DMSO did not increase the Drosophila NOS (dNOS) transcript level in calcium chelatortreated cells. Expression of recombinant COX-1 due to DMSO was diminished in cells treated with calcium chelators or channel blockers. Our results indicate that an increased intracellular calcium ion concentration due to DMSO is associated with up-regulation of the dNOS gene, leading to enhanced expression of COX-1.
목차
Abstract
1. Introduction
2. Materials and Methods
3. Results and Discussion
4. Conclusions
References
참고문헌 (28)
참고문헌 신청
1. [학술지(정기간행물)] - Moraes, A. M / 2012 / Drosophila melanogaster S2 cells for expression of heterologous genes: from gene cloning to bioprocess development / Biotechnol. Adv 30 : 613 ~ 628
2. [학술지(정기간행물)] - Angelichio, M. L / 1991 / Comparison of several promoters and polyadenylation signals for use in heterologous gene expression in cultured Drosophila cells / Nucleic Acids Res 19 : 5037 ~ 5043
3. [학술지(정기간행물)] - Maroni, G / 1986 / Molecular and cytogenetic characterization of a metallothionein gene of Drosophila / Genetics 112 : 493 ~ 504
4. [학술지(정기간행물)] - Hamer, D. H / 1986 / Metallothionein / Annu. Rev. Biochem 55 : 913 ~ 951
5. [학술대회논문] - Palmiter, R. D / 1998 / The elusive functions of metallothioneins / Proc. Natl. Acad. Sci. USA 95 : 8428 ~ 8430
2. [학술지(정기간행물)] - Angelichio, M. L / 1991 / Comparison of several promoters and polyadenylation signals for use in heterologous gene expression in cultured Drosophila cells / Nucleic Acids Res 19 : 5037 ~ 5043
3. [학술지(정기간행물)] - Maroni, G / 1986 / Molecular and cytogenetic characterization of a metallothionein gene of Drosophila / Genetics 112 : 493 ~ 504
4. [학술지(정기간행물)] - Hamer, D. H / 1986 / Metallothionein / Annu. Rev. Biochem 55 : 913 ~ 951
5. [학술대회논문] - Palmiter, R. D / 1998 / The elusive functions of metallothioneins / Proc. Natl. Acad. Sci. USA 95 : 8428 ~ 8430
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UCI(KEPA) : I410-ECN-0101-2014-400-002407760