Surgical management and results for cystic neoplasms of pancreas

Kyung Won Han; Ryun Ha; Kun Kuk Kim; Jung Nam Lee; Yeon Suk Kim; Yang Seo Koo; Yeon Ho Park

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자료유형: 학술저널

저자정보: Kyung Won Han (Gachon University Gil Medical Center) Ryun Ha (Gachon University Gil Medical Center) Kun Kuk Kim (Gachon University Gil Medical Center) Jung Nam Lee (Gachon University Gil Medical Center) Yeon Suk Kim (Gachon University Gil Medical Center) Yang Seo Koo (Gachon University Gil Medical Center) Yeon Ho Park (Gachon University Gil Medical Center)

저널정보: 한국간담췌외과학회 Annals of Hepato-Biliary-Pancreatic Surgery 한국간담췌외과학회지 제17권 제3호

발행연도: 2013.8

수록면: 118 - 125 (8page)

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Backgrounds/Aims: The diagnosis for cystic neoplasm of pancreas is based on the morphologic criteria through imaging studies, but the pre- and postoperative diagnoses are often inconsistent. This study aims at the analysis of clinical characteristics and the results of surgical treatments. Methods: A retrospective review was performed on 93 patients who have undergone surgery for pancreatic cystic diseases in our hospital from January 2001 to February 2013. Among them, 69 patients were confirmed as cystic neoplasms based on pathologic findings. Their clinical manifestations, diagnostic accuracy, surgical method and complications, pathologic findings were analyzed. Results: Serous cystic neoplasm was the most common (n=22), followed by mucinous cystic neoplasm (n=18), intraductal papillary mucinous tumor (n=11), solid pseudopapillary tumor (n=9), neuroendocrine tumor (n=7), and cystic lymphangioma (n=2). The most common clinical symptom is abdominal pains (49.3%). Preoperative imaging studies were consistent with pathological findings in 72% of patients. Cystic fluid CEA levels of 400 ng/ml or more were reliable to detect mucin secreting tumors. Pancreatoduodenectomy was performed for 13 cases and the remaining 54 patients were treated with left-side pancreatectomy. Malignancy was found in 9 cases (13%) of mucin secreting tumors; 5 cases (27.8%) in mucinous cystic neoplasm and 4 cases (36.4%) in intraductal papillary mucinous tumor. Two of these survived without recurrences during the follow-up periods. Conclusions: Exact treatment protocols for cystic neoplasm of pancreas are not decided because tumors are found with atypical forms. Surgical management is suggested for resectable tumors because a good prognosis can be expected with proper surgery if precancerous lesions are suspected at the time of discovery.

#Cystic neoplasm of pancreas #Malignancy #Surgical management

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