지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Journal of the Korean Surgical Society Vol.85 No.1
- 발행연도
- 2013.7
- 수록면
- 30 - 34 (5page)
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초록· 키워드
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Purpose: This study was designed to evaluate the efficacy of a fat clearing technique for accurate nodal staging of rectal cancer patients after preoperative chemoradiotherapy (CRT).
Methods: A total of 19 patients with rectal cancer within 10 cm from anal verge were divided into two groups: non-CRT group (n = 10) and CRT group (n = 9). For pathologic assessment, lymph node (LN) harvest was performed using conventional manual dissection followed by a fat clearing technique.
Results: A median of 3.0 additional LNs in non-CRT group and 3.8 LNs in CRT group were identified by the fat clearing technique. When subanalysis was performed in patients with fewer than 12 retrieved LNs, a median of 4.0 extra LNs in non-CRT group and 3.5 extra LNs in CRT group were identified after the fat clearing technique. None of additionally identified nodes were metastatic. In both groups, the median size of retrieved LNs following the fat clearing technique was smaller than that obtained by manual dissection (2.0 mm vs. 3.0 mm, P < 0.001).
Conclusion: The fat clearing technique allowed detection of additional LNs that were missed by the manual method, but these detected LNs were not proven to be metastatic.
Methods: A total of 19 patients with rectal cancer within 10 cm from anal verge were divided into two groups: non-CRT group (n = 10) and CRT group (n = 9). For pathologic assessment, lymph node (LN) harvest was performed using conventional manual dissection followed by a fat clearing technique.
Results: A median of 3.0 additional LNs in non-CRT group and 3.8 LNs in CRT group were identified by the fat clearing technique. When subanalysis was performed in patients with fewer than 12 retrieved LNs, a median of 4.0 extra LNs in non-CRT group and 3.5 extra LNs in CRT group were identified after the fat clearing technique. None of additionally identified nodes were metastatic. In both groups, the median size of retrieved LNs following the fat clearing technique was smaller than that obtained by manual dissection (2.0 mm vs. 3.0 mm, P < 0.001).
Conclusion: The fat clearing technique allowed detection of additional LNs that were missed by the manual method, but these detected LNs were not proven to be metastatic.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (25)
참고문헌 신청
1. [학술지(정기간행물)] - Folkesson J / 2005 / Swedish Rectal Cancer Trial: long lasting benefits from radiotherapy on survival and local recurrence rate / J Clin Oncol 23 : 5644 ~ 5650
2. [학술지(정기간행물)] - Kapiteijn E / 2001 / Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer / N Engl J Med 345 : 638 ~ 646
3. [학술지(정기간행물)] - Kim DW / 2006 / Pre-operative chemo-radiotherapy improves the sphincter preservation rate in patients with rectal cancer located within 3 cm of the anal verge / Eur J Surg Oncol 32 : 162 ~ 167
4. [학술지(정기간행물)] - Lim SB / 2012 / Longterm outcomes in patients with locally advanced rectal cancer treated with preoperative chemoradiation followed by curative surgical resection / J Surg Oncol 106 : 659 ~ 666
5. [학술지(정기간행물)] - Rodel C / 2005 / Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer / J Clin Oncol 23 : 8688 ~ 8696
2. [학술지(정기간행물)] - Kapiteijn E / 2001 / Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer / N Engl J Med 345 : 638 ~ 646
3. [학술지(정기간행물)] - Kim DW / 2006 / Pre-operative chemo-radiotherapy improves the sphincter preservation rate in patients with rectal cancer located within 3 cm of the anal verge / Eur J Surg Oncol 32 : 162 ~ 167
4. [학술지(정기간행물)] - Lim SB / 2012 / Longterm outcomes in patients with locally advanced rectal cancer treated with preoperative chemoradiation followed by curative surgical resection / J Surg Oncol 106 : 659 ~ 666
5. [학술지(정기간행물)] - Rodel C / 2005 / Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer / J Clin Oncol 23 : 8688 ~ 8696
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UCI(KEPA) : I410-ECN-0101-2014-510-002955197