Scolicidal Effects of Olea europaea and Satureja khuzestanica Extracts on Protoscolices of Hydatid Cysts

Mohammad Zibaei; Amanallah Sarlak; Bahram Delfan; Behrouz Ezatpour; Alireza Azargoon

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자료유형: 학술저널

저자정보: Mohammad Zibaei (Lorestan University of Medical Sciences) Amanallah Sarlak (Lorestan University of Medical Sciences) Bahram Delfan (Lorestan University of Medical Sciences) Behrouz Ezatpour (Lorestan University of Medical Sciences) Alireza Azargoon (Lorestan University of Medical Sciences)

저널정보: 대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.50 No.1

발행연도: 2012.2

수록면: 53 - 56 (4page)

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Treatment of hydatid disease is mainly surgical, with medical treatment being reserved as a coadjuvant treatment. Use of effective scolicidal agents during surgery of cystic echinococcosis is essential to reduce the recurrence rate. The goal of this study was to evaluate the in vitro scolicidal effects of hydroalcoholic extracts of Satureja khuzestanica leaves and aqueous extracts of Olea europaea leaves on hydatid cyst protoscolices. Echinococcus granulosus protoscolices were collected from the liver of sheep infected with the hydatid cyst. Various concentrations of plant extracts were used in different exposure times for viability assay of protoscolices. Among the olive leaf extracts tested, 0.1% and 0.01% concentrations had strong scolicidal effects in 120 min. S. khuzestanica 0.1% had very strong scolicidal effects in 30, 60, and 120 min of exposure times and the mortality rate decreased with the lower concentration. The finding have shown that the scolicidal activity of S. khuzestanica against cystic echinococosis protoscolices were more effective, while the O. europaea extract showed less effects.

#Echinococcus granulosus #Olea europaea #Satureja khuzestanica #protoscolicidal activity #hydatid cyst

참고문헌 (22)

참고문헌 신청

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