지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.6
- 수록면
- 161 - 164 (4page)
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초록· 키워드
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To evaluate the efficacy of ronidazole for treatment of Tritrichomonas foetus infection, 6 Tritrichomonas-free kittens were experimentally infected with a Korean isolate of T. foetus. The experimental infection was confirmed by direct microscopy, culture, and single-tube nested PCR, and all cats demonstrated trophozoites of T. foetus by day 20 post-infection in the feces. From day 30 after the experimentally induced infection, 3 cats were treated with ronidazole (50 mg/kg twice a day for 14 days) and 3 other cats received placebo. Feces from each cat were tested for the presence of T. foetus by direct smear and culture of rectal swab samples using modified Diamond’s medium once a week for 4 weeks. To confirm the culture results, the presence of T. foetus rRNA gene was determined by single-tube nested PCR assay. All 3 cats in the treatment group receiving ronidazole showed negative results for T. foetus infection during 2 weeks of treatment and 4 weeks follow-up by all detection methods used in this study. In contrast, rectal swab samples from cats in the control group were positive for T. foetus continuously throughout the study. The present study indicates that ronidazole is also effective to treat cats infected experimentally with a Korean isolate of T. foetus at a dose of 50 mg/kg twice a day for 14 days.
목차
등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
1. [학술지(정기간행물)] - Gookin JL / 2006 / Efficacy of ronidazole for treatment of feline Tritrichomonas foetus infection / J Vet Intern Med 20 : 536 ~ 543
2. [학술지(정기간행물)] - Foster DM / 2004 / Outcome of cats with diarrhea and Tritrichomonas foetus infection / J Am Vet Med Assoc 225 : 888 ~ 892
3. [학술지(정기간행물)] - Sun Lim / 2010 / First Report of Feline Intestinal Trichomoniasis Caused by Tritrichomonas foetus in Korea / The Korean Journal of Parasitology 48 (3) : 247 ~ 251
4. [학술지(정기간행물)] - LeVine DN / 2011 / Ronidazole pharmacokinetics after intravenous and oral immediate- release capsule administration in healthy cats / J Feline Med Surg 13 : 244 ~ 250
5. [학술지(정기간행물)] - Tolbert MK / 2009 / Tritrichomonas foetus: A new agent of feline diarrhea / Compend Contin Educ Vet 31 : 374 ~ 381
2. [학술지(정기간행물)] - Foster DM / 2004 / Outcome of cats with diarrhea and Tritrichomonas foetus infection / J Am Vet Med Assoc 225 : 888 ~ 892
3. [학술지(정기간행물)] - Sun Lim / 2010 / First Report of Feline Intestinal Trichomoniasis Caused by Tritrichomonas foetus in Korea / The Korean Journal of Parasitology 48 (3) : 247 ~ 251
4. [학술지(정기간행물)] - LeVine DN / 2011 / Ronidazole pharmacokinetics after intravenous and oral immediate- release capsule administration in healthy cats / J Feline Med Surg 13 : 244 ~ 250
5. [학술지(정기간행물)] - Tolbert MK / 2009 / Tritrichomonas foetus: A new agent of feline diarrhea / Compend Contin Educ Vet 31 : 374 ~ 381
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UCI(KEPA) : I410-ECN-0101-2014-510-002510912