지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Journal of the Korean Surgical Society Vol.84 No.5
- 발행연도
- 2013.5
- 수록면
- 267 - 272 (6page)
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초록· 키워드
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Purpose: Primary breast lymphoma is a very rare disease, accounting for 0.4?0.5% of all breast malignancies. Due to the rarity, there are only limited reports of this disease in Korean women. In this reason, we report the experience of a single institution in Korea with primary breast lymphoma (PBL). Methods: We retrospectively reviewed the medical records of 9 patients with PBL and evaluated the clinicopathologic characteristics and treatment outcomes. Results: All nine patients were female and had diffuse large B-cell lymphoma (DLBL). The median age at diagnosis was 47.9 years and the median tumor size was 3.8 cm in diameter. The most common symptom was a painless palpable mass. Five patients were classified as stage IEA and four patients were IIEA according to the Ann Arbor staging system. Four patients underwent excisional biopsy and one patient underwent a lumpectomy with sentinel lymph node biopsy due to uncertain histology of the preoperative core needle biopsy. Nine patients received anthracycline containing combined chemotherapy; among them, five patients were treated with a rituximab containing regimen. Four patients received radiotherapy combined with chemotherapy. A complete response was achieved in eight patients. During the 44 months of the median follow-up period, three cases of relapse occurred, and among them, two patients died due to disease progression. Conclusion: Most PBLs are B-cell origin, with DLBL being the most common histologic type. A combined treatment modality has been known to have positive effects on prognosis, and surgery should be limited to a diagnostic purpose.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (28)
참고문헌 신청
1. [학술지(정기간행물)] - Freeman C / 1972 / Occurrence and prognosis of extranodal lymphomas / Cancer 29 : 252 ~ 260
2. [학술지(정기간행물)] - d'Amore F / 1991 / Clinicopathological features and prognostic factors in extranodal non-Hodgkin lymphomas / Eur J Cancer 27 : 1201 ~ 1208
3. [학술지(정기간행물)] - Krol AD / 2003 / Primary extranodal non-Hodgkin's lymphoma (NHL): the impact of alternative definitions tested in the Comprehensive Cancer Centre West population-based NHL registry / Ann Oncol 14 : 131 ~ 139
4. [학술지(정기간행물)] - Ferguson DJ. / 1985 / Intraepithelial lymphocytes and macrophages in the normal breast / Virchows Arch A Pathol Anat Histopathol 407 : 369 ~ 378
5. [학술지(정기간행물)] - Topalovski M / 1999 / Lymphoma of the breast: a clinicopathologic study of primary and secondary cases / Arch Pathol Lab Med 123 : 1208 ~ 1218
2. [학술지(정기간행물)] - d'Amore F / 1991 / Clinicopathological features and prognostic factors in extranodal non-Hodgkin lymphomas / Eur J Cancer 27 : 1201 ~ 1208
3. [학술지(정기간행물)] - Krol AD / 2003 / Primary extranodal non-Hodgkin's lymphoma (NHL): the impact of alternative definitions tested in the Comprehensive Cancer Centre West population-based NHL registry / Ann Oncol 14 : 131 ~ 139
4. [학술지(정기간행물)] - Ferguson DJ. / 1985 / Intraepithelial lymphocytes and macrophages in the normal breast / Virchows Arch A Pathol Anat Histopathol 407 : 369 ~ 378
5. [학술지(정기간행물)] - Topalovski M / 1999 / Lymphoma of the breast: a clinicopathologic study of primary and secondary cases / Arch Pathol Lab Med 123 : 1208 ~ 1218
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UCI(KEPA) : I410-ECN-0101-2014-510-003543526