?;?;Objectives: Recently, Korean medicine has been explored by employing mathematical methods, which is an effort to raise Korean medicine to a higher level of scientific research. In that vein, we propose a mathematical model, analyzing the effects of seasonal cycle as an external factor in addition to the internal interactions of five-states, the engendering and the restraining.
?;?;Methods: Some modified differential equations with 5-state variables were given to describe the interactions of the engendering and the restraining, and effect of seasonal cycle, and are numerically analyzed by Runge-Kutta method. We then simulated it along with time and dynamically analyzed it by Moran's I, a spatial autocorrelation.
?;?;Results: We showed the effects of seasonal cycle on yin-yang five-states and applied it to the human life cycle.
?;?;Conclusions: Our result is comparable to previous results in the respect that we consider the seasonal cycle and its effect on five-states, unlike others' mainly focusing on internal interaction. Furthermore, we suggest some follow-up study taking into consideration the complexity and diversity of external factors.