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논문 기본 정보

자료유형
학술저널
저자정보
Byung-Gwan Choi (Chonnam National University) Choong-Young Kim (Chonnam National University) Seung-Hyun Cho (Chonnam National University) Hee-Joon Kim (Chonnam National University) Yang-Seok Koh (Chonnam National University) Jung-Chul Kim (Chonnam National University) Chol-Kyoon Cho (Chonnam National University) Hyun-Jong Kim (Chonnam National University) Young-Hoe Hur (Chonnam National University)
저널정보
대한외과학회 Annals of Surgical Treatment and Research Journal of the Korean Surgical Society Vol.84 No.3
발행연도
2013.3
수록면
168 - 177 (10page)

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Purpose: It is increasingly being recognized that the lymph node ratio (LNR) is an important prognostic factor for gallbladder carcinoma patients. The present study evaluated predictors of tumor recurrence and survival in a large, mono-institutional cohort of patients who underwent surgical resection for gallbladder carcinoma, focusing specifically on the prognostic value of lymph node (LN) status and of LNR in stage IIIB patients. Methods: Between 2004 and 2011, 123 patients who underwent R0 radical resection for gallbladder carcinoma at the Chonnam National University Hwasun Hospital were reviewed retrospectively. Patients were staged according to the American Joint Committee on Cancer 7th edition, and prognostic factors affecting disease free survival, such as age, sex, comorbidity, body mass index, presence of preoperative symptoms, perioperative blood transfusion, postoperative complications, LN dissection, tumor size, differentiation, lymph-vascular invasion, perineural invasion, T stage, presence of LN involvement, N stage, numbers of positive LNs, LNR and implementation of adjuvant chemotherapy, were statistically analyzed. Results: LN status was an important prognostic factor in patients undergoing curative resection for gallbladder carcinoma. The total number of LNs examined was implicated with prognosis, especially in N0 patients. LNR was a powerful predictor of disease free survival even after controlling for competing risk factors, in curative resected gallbladder cancer patients, and especially in stage IIIB patients. Conclusion: LNR is confirmed as an independent prognostic factor in curative resected gallbladder cancer patients, especially in stage IIIB gallbladder carcinoma.
#Lymph node ratio #Gallbladder #Carcinoma #Stage IIIB

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INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES

참고문헌 (30)

참고문헌 신청
1. [학술지(정기간행물)] - Shirai Y / 2007 / Radical lymph node dissection for gallbladder cancer: indications and limitations / Surg Oncol Clin N Am 16 : 221 ~ 232 google schola 2. [단행본] - Edge SB / 2010 / AJCC cancer staging manual. 7th ed / Springer google schola 3. [단행본] - Japanese Society of Biliary Surgery / 2004 / Classification of biliary tract carcinoma. 2nd ed / Kanehara google schola 4. [학술지(정기간행물)] - Benoist S / 1998 / Long-term results after curative resection for carcinoma of the gallbladder. French University Association for Surgical Research / Am J Surg 175 : 118 ~ 122 google schola 5. [학술지(정기간행물)] - Tsukada K / 1997 / Lymph node spread from carcinoma of the gallbladder / Cancer 80 : 661 ~ 667 google schola

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