지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Journal of the Korean Surgical Society Vol.84 No.4
- 발행연도
- 2013.4
- 수록면
- 245 - 251 (7page)
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초록· 키워드
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Purpose: There is controversy concerning the effect of a positive T-lymphocytotoxic crossmatch (TLC) on clinical outcomes in adult living donor liver transplantation (LDLT). The aim of this study was to investigate the effect of TLC on clinical outcomes in LDLT and to determine how long a pretransplant positive TLC continues after liver transplantation (LT). Methods: Between January 2005 and June 2010, 219 patients underwent adult LDLT at National Cancer Center. The TLC test was routinely performed before LDLT. TLC test results were positive in 8 patients (3.7%). Patients were divided into 2 groups according to the result of TLC: positive TLC (n = 8) and negative TLC (n = 211) groups. All patients with a pretransplant positive TLC (n = 6) underwent a TLC test every week until negative conversion of TLC, except 2 patients who refused to receive the TLC test. Results: Acute cellular rejection, surgical complications and patient or graft survival were not significantly different between both groups. All patients with a positive TLC (n = 6) had a posttransplant negative TLC. The median time to negative conversion of TLC was 1.5 weeks (range, 1 to 3 weeks). Conclusion: A pretransplant positive TLC does not affect clinical outcomes in adult LDLT. Moreover, T-lymphocytotoxic cross-reactivity disappeared within 3 weeks (range, 1 to 3 weeks) after LT.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (28)
참고문헌 신청
1. [학술지(정기간행물)] - Castillo-Rama M / 2008 / Preformed antibodies detected by cytotoxic assay or multibead array decrease liver allograft survival: role of human leukocyte antigen compatibility / Liver Transpl 14 : 554 ~ 562
2. [학술지(정기간행물)] - Muro M / 2005 / Liver recipients harbouring anti-donor preformed lymphocytotoxic antibodies exhibit a poor allograft survival at the first year after transplantation: experience of one centre / Transpl Immunol 14 : 91 ~ 97
3. [학술지(정기간행물)] - Iwatsuki S / 1984 / Liver transplantation against T cell-positive warm crossmatches / Transplant Proc 16 : 1427 ~ 1429
4. [학술지(정기간행물)] - Iwatsuki S / 1981 / Successful liver transplantation from crossmatch- positive donors / Transplant Proc 13 (1 Pt 1) : 286 ~ 288
5. [학술지(정기간행물)] - Takaya S / 1992 / The adverse impact on liver transplantation of using positive cytotoxic crossmatch donors / Transplantation 53 : 400 ~ 406
2. [학술지(정기간행물)] - Muro M / 2005 / Liver recipients harbouring anti-donor preformed lymphocytotoxic antibodies exhibit a poor allograft survival at the first year after transplantation: experience of one centre / Transpl Immunol 14 : 91 ~ 97
3. [학술지(정기간행물)] - Iwatsuki S / 1984 / Liver transplantation against T cell-positive warm crossmatches / Transplant Proc 16 : 1427 ~ 1429
4. [학술지(정기간행물)] - Iwatsuki S / 1981 / Successful liver transplantation from crossmatch- positive donors / Transplant Proc 13 (1 Pt 1) : 286 ~ 288
5. [학술지(정기간행물)] - Takaya S / 1992 / The adverse impact on liver transplantation of using positive cytotoxic crossmatch donors / Transplantation 53 : 400 ~ 406
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UCI(KEPA) : I410-ECN-0101-2014-510-003019594