지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Journal of the Korean Surgical Society Vol.84 No.4
- 발행연도
- 2013.4
- 수록면
- 195 - 201 (7page)
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초록· 키워드
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Purpose: Regional lymph node (LN) metastases are detected in 57?85% of patients with papillary thyroid carcinoma (PTC) and are associated with increased tumor recurrence. However, the management of lymphatic disease in patients with PTC has been ongoing source of debate. We have prospectively assessed the usefulness and accuracy of sentinel LN (SLN) biopsy for the detection of LN metastases in patients with PTC on preoperative imaging using single photon emission computed tomography/computed tomography (SPECT/CT) and 99mTc phytate. Methods: We prospectively assessed 39 patients with PTC who had risk factors for recurrence or with the necessity of intraoperative LN sampling for suspicious LN metastases on preoperative imaging from August 2010 to March 2011. The patients underwent preoperative lymphoscintigraphy and SPETC/CT and intraoperative SLN biopsy (SLNB). Results: 99mTc lymphoscintigraphy and SPECT/CT localized SLN in 38 patients (97.4%), with the gamma probe identifying 2.15 mean SLNs in the lateral neck of the 39 patients. Skip metastasis was found in one patient, and lateral compartment LN metastasis in 17 (43.5%). The sensitivity, specificity, and accuracy of SLNB for lateral compartment LN metastasis were 88.2%, 100%, and 94.8%, respectively. SLNB was more accurate and useful for lateral than for central compartment LN metastasis. Conclusion: SPECT/CT improved SLN detection and anatomical localization compared with lymphoscintigraphy. SLNB in patients with risk factors for recurrence or the necessity of intraoperative LN sampling for suspected LN metastases on preoperative imaging was accurate in detecting LN metastases and may help in deciding whether to perform lateral compartment dissection in patients with PTC.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (30)
참고문헌 신청
1. [학술지(정기간행물)] - Ronckers CM / 2005 / Thyroid cancer and multiple primary tumors in the SEER cancer registries / Int J Cancer 117 : 281 ~ 288
2. [인터넷자원] - National Cancer Information Center / / Cancer facts & figures 2012 in the republic of Korea
3. [학술지(정기간행물)] - King AD / 2008 / Imaging for staging and management of thyroid cancer / Cancer Imaging 8 : 57 ~ 69
4. [학술지(정기간행물)] - Machens A / 2002 / Pattern of nodal metastasis for primary and reoperative thyroid cancer / World J Surg 26 : 22 ~ 28
5. [학술지(정기간행물)] - Mazzaferri EL / 1994 / Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer / Am J Med 97 : 418 ~ 428
2. [인터넷자원] - National Cancer Information Center / / Cancer facts & figures 2012 in the republic of Korea
3. [학술지(정기간행물)] - King AD / 2008 / Imaging for staging and management of thyroid cancer / Cancer Imaging 8 : 57 ~ 69
4. [학술지(정기간행물)] - Machens A / 2002 / Pattern of nodal metastasis for primary and reoperative thyroid cancer / World J Surg 26 : 22 ~ 28
5. [학술지(정기간행물)] - Mazzaferri EL / 1994 / Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer / Am J Med 97 : 418 ~ 428
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UCI(KEPA) : I410-ECN-0101-2014-490-003019528