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논문 기본 정보

자료유형
학술저널
저자정보
Seung-whan Oh (Kyung Hee University) Bong-ha Ryu (Kyung Hee University)
저널정보
대한한의학회 대한한의학회지 대한한의학회지 제32권 제6호
발행연도
2011.11
수록면
54 - 66 (13page)

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초록· 키워드

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Objectives: The purpose of the present study was to investigate the antidiarrheal effects of Anjang-san in mice and rats.
Methods: We measured the content of condensed tannin in Anjang-san extract, and observed the effects of Anjang-san on the small intestinal and colonic transport of mice, as well as on mice models of diarrhea induced by castor oil and MgSO4, and on rat models of castor oil-induced enteropooling.
Results: Anjang-san showed significant inhibitory effects on abnormally increased small intestinal transit induced by pyridostigmine and neostigmine, and inhibitory effects on large intestinal transit. Anjang-san also exhibited antidiarrheal effects on diarrhea induced by MgSO4, and inhibitory effects on castor oil-induced enteropooling. Anjang-san also improved castor oil-induced diarrhea based on simple numbers without statistical significance.
Conclusion: These results demonstrate that Anjang-san has significant antidiarrheal properties and attests to its possible utility in functional diarrheas, irritable bowel syndrome and other gastrointestinal disorders based upon further studies.

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Introduction
Materials and Methods
Results
Discussion
Conclusions
References

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UCI(KEPA) : I410-ECN-0101-2014-519-000273099