지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objectives: This study was designed to evaluate lipid-lowering and antioxidant effects of Artemisia capillaris(A. capillaris) using a model of hyperlipidemic rats induced by poloxamer-407.
Methods: Rats were previously treated by A. capillaris water extract, and intraperitoneally injected by poloxamer-407 to induce hyperlipidemia. Parameters of serum lipid and oxidative stress biomarkers were determined.
Results:
1. A. capillaris ameliorated the elevation of serum total cholesterol, triglyceride, LDL-cholesterol and MDA level.
2. A. capillaris ameliorated the reduction of serum TAC and SOD activities.
3. A. capillaris ameliorated the reduction of serum GSH and GSH-reductase level.
Conclusions: According to these results, A. capillaris can be used to treat hyperlipidemia or as basis for making new drugs for treating hyperlipidemia in the future.
Methods: Rats were previously treated by A. capillaris water extract, and intraperitoneally injected by poloxamer-407 to induce hyperlipidemia. Parameters of serum lipid and oxidative stress biomarkers were determined.
Results:
1. A. capillaris ameliorated the elevation of serum total cholesterol, triglyceride, LDL-cholesterol and MDA level.
2. A. capillaris ameliorated the reduction of serum TAC and SOD activities.
3. A. capillaris ameliorated the reduction of serum GSH and GSH-reductase level.
Conclusions: According to these results, A. capillaris can be used to treat hyperlipidemia or as basis for making new drugs for treating hyperlipidemia in the future.
목차
Introduction
Materials and Methods
Results
Discussion
Conclusion
References
참고문헌 (46)
참고문헌 신청
1. [학술지(정기간행물)] - Jain KS / 2007 / The biology and chemistry of hyperlipidemia / Bioorganic & Medicinal Chemistry 15 (14) : 4674 ~ 4699
2. [학술지(정기간행물)] - Rosen IM / 2006 / Sams RW 2nd / Common questions in managing hyperlipidemia 33 (4) : 903 ~ 921
3. [학술지(정기간행물)] - Fowler SB / 2006 / Johnson-Wells D. Management of lipid disorders for stroke prevention / Journal of Neuroscience Nursing 38 : 282 ~ 287
4. [학술지(정기간행물)] - Castilla-Guerra L / 2009 / Secondary stroke prevention in the elderly: new evidence in hypertension and hyperlipidemia / European Journal of Internal Medicine 20 (6) : 586 ~ 590
5. [학술지(정기간행물)] - Mangin EF / 2004 / Comparing hyperlipidemia control with daily versus twice-weekly simvastatin / Annals of Pharmacotherapy 38 (11) : 1789 ~ 1793
2. [학술지(정기간행물)] - Rosen IM / 2006 / Sams RW 2nd / Common questions in managing hyperlipidemia 33 (4) : 903 ~ 921
3. [학술지(정기간행물)] - Fowler SB / 2006 / Johnson-Wells D. Management of lipid disorders for stroke prevention / Journal of Neuroscience Nursing 38 : 282 ~ 287
4. [학술지(정기간행물)] - Castilla-Guerra L / 2009 / Secondary stroke prevention in the elderly: new evidence in hypertension and hyperlipidemia / European Journal of Internal Medicine 20 (6) : 586 ~ 590
5. [학술지(정기간행물)] - Mangin EF / 2004 / Comparing hyperlipidemia control with daily versus twice-weekly simvastatin / Annals of Pharmacotherapy 38 (11) : 1789 ~ 1793
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UCI(KEPA) : I410-ECN-0101-2014-519-000272830