지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objectives: Coptidis Rhizoma is one of the most popular and multi-purpose herbs in traditional medicine. The purpose of this study was to contribute to research and applications of Coptidis Rhizoma in clinic, by analyzing and reviewing international studies on its chemical compositions and pharmacological effects.
Methods: This study analyzed 344 articles published from 2000 to 2010 in PubMed, Refworks, Riss, and KTKP. The search keywords were “Coptis chinensis”, “Coptis japonica”, “Coptidis Rhizoma”, “huanglian” and “huanglian in Chinese”. From them, we selected 114 articles which met our inclusion criteria.
Results: This study reviewed 114 articles on Coptidis Rhizoma and its active components in terms of "Active components", "Experimental studies", "Clinical studies", "Industrial use" and "Side Effects/Toxicity".
Conclusions: The active components of Coptidis Rhizoma are berberine, coptisine, epiberberine, palmatine, jateorrhizine, magnoflorine, worenine, etc. It is reported that Coptidis Rhizoma and its active components have anti-inflammatory, antibacterial, antitumor, and antioxidant activity, and cardiovascular, hepatoprotective, antidiabetic, neuroprotective, gastrointestinal, pain relieving, discharge phlegm and metrocyte proliferation effects. Moreover, we found that Coptidis Rhizoma can be used for bath preparation, cosmetic products and as a natural antimicrobial substance.
Methods: This study analyzed 344 articles published from 2000 to 2010 in PubMed, Refworks, Riss, and KTKP. The search keywords were “Coptis chinensis”, “Coptis japonica”, “Coptidis Rhizoma”, “huanglian” and “huanglian in Chinese”. From them, we selected 114 articles which met our inclusion criteria.
Results: This study reviewed 114 articles on Coptidis Rhizoma and its active components in terms of "Active components", "Experimental studies", "Clinical studies", "Industrial use" and "Side Effects/Toxicity".
Conclusions: The active components of Coptidis Rhizoma are berberine, coptisine, epiberberine, palmatine, jateorrhizine, magnoflorine, worenine, etc. It is reported that Coptidis Rhizoma and its active components have anti-inflammatory, antibacterial, antitumor, and antioxidant activity, and cardiovascular, hepatoprotective, antidiabetic, neuroprotective, gastrointestinal, pain relieving, discharge phlegm and metrocyte proliferation effects. Moreover, we found that Coptidis Rhizoma can be used for bath preparation, cosmetic products and as a natural antimicrobial substance.
목차
서론
연구방법
결과
고찰
결론
참고문헌
참고문헌 (114)
참고문헌 신청
1. [단행본] - 전국한의과대학 공통교재편찬위원회 / 2008 / 본초학 / 영림사 : 218 ~ 220
2. [학술지(정기간행물)] - Shin HS / 1997 / Effects of Rhizorna Coptidis on Cellular Activity and IL-6 Production of LPS-treated Periodontal Ligarnent Cells / Journal of Wonkwang dental Research institute 7 (1) : 177 ~ 191
3. [단행본] - 山原條二 / 1976 / 황련 및 그의 함유성분의 중추억제 작용, In Berberine형 알칼로이드의 행동약리학적 연구(제1판) / 日藥理誌 : 899 ~ 908
4. [학술지(정기간행물)] - Tang J / 2009 / Berberine and Coptidis rhizoma as novel antineoplastic agents : a review of traditional use and biomedical investigations / Journal of Ethnopharmacology 126 (1) : 5 ~ 17
5. [학술지(정기간행물)] - Liu F / 2000 / Antioxidative and free radical scavenging activities of selected medicinal herbs / Life Sciences 66 (8) : 725 ~ 735
2. [학술지(정기간행물)] - Shin HS / 1997 / Effects of Rhizorna Coptidis on Cellular Activity and IL-6 Production of LPS-treated Periodontal Ligarnent Cells / Journal of Wonkwang dental Research institute 7 (1) : 177 ~ 191
3. [단행본] - 山原條二 / 1976 / 황련 및 그의 함유성분의 중추억제 작용, In Berberine형 알칼로이드의 행동약리학적 연구(제1판) / 日藥理誌 : 899 ~ 908
4. [학술지(정기간행물)] - Tang J / 2009 / Berberine and Coptidis rhizoma as novel antineoplastic agents : a review of traditional use and biomedical investigations / Journal of Ethnopharmacology 126 (1) : 5 ~ 17
5. [학술지(정기간행물)] - Liu F / 2000 / Antioxidative and free radical scavenging activities of selected medicinal herbs / Life Sciences 66 (8) : 725 ~ 735
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UCI(KEPA) : I410-ECN-0101-2014-519-000272714