지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives: This study was performed in order to investigate the anti-hemolytic effect of Chunghyuljihwang-tang (CHJHT, Qingxuedihuang-tang) on phenylhydrazine-induced hemolytic anemia in Rats.
Materials and Methods: Hemolytic anemia model of rats were induced by phenylhydrazine(PHZ, 40mg/kg/day, i.p.) for 3days. Male Sprague-Dawley rats were divided into three groups for their treatment. Normal group was injected normal saline for 3 days with distilled water(d.w.) orally, control group was injected PHZ for 3 days with d.w. and CHJHT group was injected PHZ for 3 days with administration of CHJHT for 10 days. RBC(Red blood cell), Hb(hemoglobin), mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, reticulocyte were determined on day 0, 4, 7, 10. Body weight was investigated on day 0, 2, 4, 6, 8, 10 and the weight of spleen was measured on day 10.
Results: For CHJHT group, the levels of RBC and Hb were significantly higher than control group on day 4, and the concentration of hemoglobin on day 7 was increased more than control group. Moreover, reticulocyte was significantly decreased on day 10 more than control group. These results could be concluded that CHJHT suppressed the hemolytic anemia by PHZ and improved hematological values of anemia earlier.
Materials and Methods: Hemolytic anemia model of rats were induced by phenylhydrazine(PHZ, 40mg/kg/day, i.p.) for 3days. Male Sprague-Dawley rats were divided into three groups for their treatment. Normal group was injected normal saline for 3 days with distilled water(d.w.) orally, control group was injected PHZ for 3 days with d.w. and CHJHT group was injected PHZ for 3 days with administration of CHJHT for 10 days. RBC(Red blood cell), Hb(hemoglobin), mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, reticulocyte were determined on day 0, 4, 7, 10. Body weight was investigated on day 0, 2, 4, 6, 8, 10 and the weight of spleen was measured on day 10.
Results: For CHJHT group, the levels of RBC and Hb were significantly higher than control group on day 4, and the concentration of hemoglobin on day 7 was increased more than control group. Moreover, reticulocyte was significantly decreased on day 10 more than control group. These results could be concluded that CHJHT suppressed the hemolytic anemia by PHZ and improved hematological values of anemia earlier.
목차
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方法
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結論
參考文獻
참고문헌 (20)
참고문헌 신청
1. [학술지(정기간행물)] - Bruner AB / 1996 / Randomized study of cognitive effects of iron supplementation in non-anemic iron deficient adolescent girls / Lancet 348 : 992 ~ 996
2. [학술지(정기간행물)] - Choi CW / 2003 / Diagnosis and treatment of anemia. An out-patient approach / J Korean Acad Fam Med 24 (303) : 311 ~
3. [학술지(정기간행물)] - Dhaliwal G / 2004 / Hemolytic anemia / Am Fam Physician 69 (11) : 1599 ~ 1606
4. [학술지(정기간행물)] - 하정옥 / 2007 / 소아 용혈빈혈(Hemolytic anemia in pediatrics) / Korean Journal of Pediatrics 50 (6) : 511 ~ 518
5. [단행본] - 전국간계내과학 교수 / 2001 / 간계내과학 / 서울:동 양의학연구원출판부 : 169 ~ 551
2. [학술지(정기간행물)] - Choi CW / 2003 / Diagnosis and treatment of anemia. An out-patient approach / J Korean Acad Fam Med 24 (303) : 311 ~
3. [학술지(정기간행물)] - Dhaliwal G / 2004 / Hemolytic anemia / Am Fam Physician 69 (11) : 1599 ~ 1606
4. [학술지(정기간행물)] - 하정옥 / 2007 / 소아 용혈빈혈(Hemolytic anemia in pediatrics) / Korean Journal of Pediatrics 50 (6) : 511 ~ 518
5. [단행본] - 전국간계내과학 교수 / 2001 / 간계내과학 / 서울:동 양의학연구원출판부 : 169 ~ 551
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UCI(KEPA) : I410-ECN-0101-2014-519-000285091