지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objectives: Sahyangsohapwon (SS) is a herbal medication that has been widely used with circulatory and neural diseases. This study was conducted to assess the effect of SS on the autonomic nervous system by using heart rate variability measurement.
Methods: The eligible subjects were enrolled from the healthy male group of ages 20 to 35 years. They were divided into two groups, the SS group (n=26) and the control (n=24). We monitored the ECG of subjects from the time period 14:00 to 18:00. In the SS group, subjects were administered with a dose of SS at the time 15:00, whereas the control group had none. For each hour HRV measurement was monitored every 15 minutes for 512 seconds from the time period 14:00 to 18:00. The mean value, which was calculated using the 4 values during each hour (i.e. 14:00, 14:15, 14:30, 14:45), was used as the representative value for each individual hour. For the measurement values, RR-interval and SDNN (standard deviation of the NN intervals) were used as time domain analysis, and HF (high frequency), LF (low frequency), and LF/HF ratio were used as frequency domain analysis.
Results: The LF value showed an increase after one hour of SS administration and showed gradual diminution for each and every hour. The repeated measures of ANOVA for the comparison of the LF value between the SS group and the control group showed significant differences. While, RR interval, SDNN, HF, and LF/HF ratio values showed no significant differences between the two groups.
Conclusions: We suggest that the SS might be useful for stabilizing autonomic nervous system by inhibiting sympathetic nerve activation in healthy people.
Methods: The eligible subjects were enrolled from the healthy male group of ages 20 to 35 years. They were divided into two groups, the SS group (n=26) and the control (n=24). We monitored the ECG of subjects from the time period 14:00 to 18:00. In the SS group, subjects were administered with a dose of SS at the time 15:00, whereas the control group had none. For each hour HRV measurement was monitored every 15 minutes for 512 seconds from the time period 14:00 to 18:00. The mean value, which was calculated using the 4 values during each hour (i.e. 14:00, 14:15, 14:30, 14:45), was used as the representative value for each individual hour. For the measurement values, RR-interval and SDNN (standard deviation of the NN intervals) were used as time domain analysis, and HF (high frequency), LF (low frequency), and LF/HF ratio were used as frequency domain analysis.
Results: The LF value showed an increase after one hour of SS administration and showed gradual diminution for each and every hour. The repeated measures of ANOVA for the comparison of the LF value between the SS group and the control group showed significant differences. While, RR interval, SDNN, HF, and LF/HF ratio values showed no significant differences between the two groups.
Conclusions: We suggest that the SS might be useful for stabilizing autonomic nervous system by inhibiting sympathetic nerve activation in healthy people.
목차
서론
연구방법
연구결과
고찰
결론
참고문헌
참고문헌 (18)
참고문헌 신청
1. [학술지(정기간행물)] - Theorell T / 1975 / Ballistocardiographic indicators of prognosis in ischemic heart disease / J Lab Clin Med 86 (1) : 46 ~ 56
2. [학술지(정기간행물)] - Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology / 1996 / Heart rate variability. Standards of measurement, physiological interpretation, and clinical use / Eur Heart J 17 (3) : 354 ~ 381
3. [학술지(정기간행물)] - Yeragani VK / 1991 / Heart rate variability in patients with major depression / Phychiatry Res 37 : 35 ~ 46
4. [단행본] - Jin SM / 1975 / Taepunghyemin-whajegugbang / Sunpoong : 3 ~
5. [학술지(정기간행물)] - Nam SK / 1990 / Experimental Studies on the Effects of Woowhangchungsimwon and Sohaphyangwon
2. [학술지(정기간행물)] - Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology / 1996 / Heart rate variability. Standards of measurement, physiological interpretation, and clinical use / Eur Heart J 17 (3) : 354 ~ 381
3. [학술지(정기간행물)] - Yeragani VK / 1991 / Heart rate variability in patients with major depression / Phychiatry Res 37 : 35 ~ 46
4. [단행본] - Jin SM / 1975 / Taepunghyemin-whajegugbang / Sunpoong : 3 ~
5. [학술지(정기간행물)] - Nam SK / 1990 / Experimental Studies on the Effects of Woowhangchungsimwon and Sohaphyangwon
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UCI(KEPA) : I410-ECN-0101-2014-519-000284347