Life, aging, diseases and death we cannot avoid in our lives. Among them, diseases are the ones that people want to avoid because they are the most painful. For ancient people, they lacked knowledge of diseases or medicine so they only could pray for healing as they looked at patients rolling and groaning. Because there was no way to cure the diseases, their anguish and fear must be much stronger than what we experience now. People in Shang Dynasty of China also asked the causes and healing of diseases by practicing divination because they had extreme fear for diseases. We can have somewhat understanding of diseases and treatments that people in Shang Dynasty had by looking at oracle bones inscription. Based on the information, this study examines causes, types, conditions, treatments and prevention of fourteen disease among diseases in the inscription. Several characteristics of the diseases are as follows; Firstly, in examination of inscription related to diseases, people in Shang Dynasty classified diseases in very detail and had advanced consciousness including different practices of divination according to symptoms or nature of diseases. Secondly, in inscribing diseases in oracle bones, generally people in Shang Dynasty added a letter that shows the part affected by diseases to the letter 疾which means disease as stated below. 1. 疾首(Jilsu) - diseases in the head 2. 疾目(Jilmok) - diseases in eyes 3. 疾耳(Jilee) - diseases in ears 4. 疾自(Jilja) - diseases in the nose 5. 疾舌(Jilseol) - diseases in the tongue 6. 疾言(Jileon) - diseases in the throat 7. 疾口(Jilgu) - diseases in the mouth 8. 疾齒(Jilchi) - diseases in teeth 9. 疾身(Jilsin) - diseases in the trunk 10. 疾腹(Jilbok) - diseases in the stomach 11. 疾心(Jilsim) - diseases in the heart 12. 疾肩(Jilkyeon) - diseases in the shoulders 13. 疾臂(Jilbi) - diseases in the arms 14. 疾疋(Jilso) - diseases in the legs Thirdly, people in Shang Dynasty expressed the name of diseases as their symptoms, and through this, it is understood that the level of medical treatment was significantly advanced in Shang Dynasty. The words that express the name of diseases as their symptoms are as follows; 1. ??????(conjunctivitis) - a symptom of eyes with bloodshot like flares because of high fever 2. ??(nasal polyp) - a symptom of the nose with nasal discharge or bleeding because of fat in nostril 3. ??(dumbness) - a symptom of losing speech because of hard tongue like stone 4. ??(dumbness) - a symptom of losing speech because of losing sound from the throat (the part of vocal cord) due to its abnormality 5. ????(facial nerve palsy) - a symptom of the mouth being twisted to one side out of shape because of paralysis of facial nerve caused by stroke 6. ??(coronal discoloration) - a symptom of teeth changing into black 7. ????(palpitation) - a symptom of the heart palpitating abnormally Thus, we can understand that people in Shang Dynasty suffered several diseases through oracle bones inscription. In addition, according to the symptoms of each disease, they cured them with various methods of treatment, which shows that it was their longing hope that they wanted to maintain their healthy life.