지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.12
- 수록면
- 147 - 154 (8page)
이용수
초록· 키워드
오류제보하기
Objectives：Recently, repetitive transcranial magnetic stimulation(rTMS) has been used clinically in the treatment of refractory mood disorder, schizophrenia and anxiety disorder. There are many alcohol dependent patients who suffer from depression. Therefore, the aim of this study was to investigate the effects of rTMS on depression in alcohol dependent patients.
Methods：Sixteen alcohol dependent patients with depression(16 males ; age range : 30-61 ; mean age : 45.06± 8.83 years)were given rTMS on the left dorsolateral prefrontal cortex at a high frequency(10 Hz) for 10-minute-durations each day for 2weeks. Before rTMS was applied, patients had been screened by using a Transcranial magnetic stimulation adult safety screen(TASS, Keel et al) to exclude contraindication. We evaluated changes in BDI and HRSD scores between pre- and post-rTMS treatment.
Results：While the mean BDI and HRSD score were 21.56±7.81, 17.81±6.68 before rTMS, after rTMS the mean BDI and HRSD score went down to 9.44±7.34, 3.81±2.59. Accordingly, the difference in score between pre- ; and post-rTMS was statistically significant in both BDI(t=6.86, p=0.000) and HRSD(t=9.92, p=0.000).
Conclusion：These results suggest that rTMS seems to be effective for the treatment of depressive symptoms of alcohol dependent patients. However, we didn’t have a control group which was given false stimulation(a placebo). The sample size of the study was too small. The next study complements these limitations of this study and will need further research.
Methods：Sixteen alcohol dependent patients with depression(16 males ; age range : 30-61 ; mean age : 45.06± 8.83 years)were given rTMS on the left dorsolateral prefrontal cortex at a high frequency(10 Hz) for 10-minute-durations each day for 2weeks. Before rTMS was applied, patients had been screened by using a Transcranial magnetic stimulation adult safety screen(TASS, Keel et al) to exclude contraindication. We evaluated changes in BDI and HRSD scores between pre- and post-rTMS treatment.
Results：While the mean BDI and HRSD score were 21.56±7.81, 17.81±6.68 before rTMS, after rTMS the mean BDI and HRSD score went down to 9.44±7.34, 3.81±2.59. Accordingly, the difference in score between pre- ; and post-rTMS was statistically significant in both BDI(t=6.86, p=0.000) and HRSD(t=9.92, p=0.000).
Conclusion：These results suggest that rTMS seems to be effective for the treatment of depressive symptoms of alcohol dependent patients. However, we didn’t have a control group which was given false stimulation(a placebo). The sample size of the study was too small. The next study complements these limitations of this study and will need further research.
목차
서론
대상 및 방법
결과
고찰
참고문헌
참고문헌 (46)
참고문헌 신청
1. [학술지(정기간행물)] - Barker AT / 1985 / Non-invasive magnetic stimulation of the human motor cortex / Lancet 1 : 1106 ~ 1107
2. [단행본] - Bohning DE / 2000 / Introduction and overview of TMS physics, In Transcranial magnetic stimulation in neuropsychiatry / American Psychiatric Press : 13 ~ 44
3. [학술지(정기간행물)] - George MS / 1999 / Transcranial Magnetic Stimulation: application in neuropsychiatry / Archives of General Psychiatry 56 : 300 ~ 311
4. [학술지(정기간행물)] - Wassermann EM / 1996 / Use and safety of a new repetitive transcranial magnetic stimulator / Electroencephalography and Clinical Neurophysiology/Electromyography and Motor Control 101 : 412 ~ 417
5. [학술지(정기간행물)] - 채정호 / 2001 / 경두개 자기 자극(Transcranial Magnetic Stimulation)의 신경정신과적 응용 / 신경정신의학 40 (1) : 3 ~ 11
2. [단행본] - Bohning DE / 2000 / Introduction and overview of TMS physics, In Transcranial magnetic stimulation in neuropsychiatry / American Psychiatric Press : 13 ~ 44
3. [학술지(정기간행물)] - George MS / 1999 / Transcranial Magnetic Stimulation: application in neuropsychiatry / Archives of General Psychiatry 56 : 300 ~ 311
4. [학술지(정기간행물)] - Wassermann EM / 1996 / Use and safety of a new repetitive transcranial magnetic stimulator / Electroencephalography and Clinical Neurophysiology/Electromyography and Motor Control 101 : 412 ~ 417
5. [학술지(정기간행물)] - 채정호 / 2001 / 경두개 자기 자극(Transcranial Magnetic Stimulation)의 신경정신과적 응용 / 신경정신의학 40 (1) : 3 ~ 11
이 논문의 저자 정보
이 논문과 함께 이용한 논문
대사증후군 환자에서 영양소 섭취 상태와 우울증과의 연관성 : 2014년 국민건강영양조사 자료를 이용하여
김자형
,
한아름
,
신새론
외 1명
농촌의학·지역보건
2017
.06
대규모 신경망의 관점에서 본 우울증
김양태
생물치료정신의학
2017
.02
한국인에서 흡연과 우울증상의 연관성
성한나
,
김종성
보건교육건강증진학회지
2016
.06
일개 전자산업 여성 근로자에서 혈중 비타민D와 우울증상과의 관계
권순일
,
김영욱
,
채창호
외 2명
대한직업환경의학회 학술대회 논문집
2014
.11
혈관성 우울증의 개념, 병인기전, 치료와 예후
김병수
생물치료정신의학
2014
.04
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2014-513-000468483