지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Journal of the Korean Surgical Society Vol.83 No.5
- 발행연도
- 2012.11
- 수록면
- 281 - 287 (7page)
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초록· 키워드
오류제보하기
Purpose: The safety and the feasibility of performing laparoscopic surgery for rectal cancer after preoperative chemoradiotherapy (CRT) have not yet been established. Thus, the aim of this study was to evaluate the efficacy and the safety of laparoscopic rectal cancer surgery performed after preoperative CRT. Methods: We enrolled 124 consecutive patients who underwent laparoscopic surgery for rectal cancer. Of these patients, 56 received preoperative CRT (CRT group), whereas 68 did not (non-CRT group). The patients who were found to have distant metastasis and open conversion during surgery were excluded. The clinicopathologic parameters were evaluated and the short-term outcomes were compared between the CRT and non-CRT groups. Results: The mean operation time was longer in the CRT group (294 minutes; range, 140 to 485 minutes; P = 0.004). In the non-CRT group, the tumor sizes were larger (mean, 4.0 cm; range, 1.2 to 8.0 cm; P ＜ 0.001) and more lymph nodes were harvested (mean, 12.9; range, 0 to 35; P ＜ 0.001). However, there was no significant difference between the two groups in time to first bowel movement, tolerance of a soft diet, length of hospital stay, and postoperative complication rate. Conclusion: Performing laparoscopic surgery for rectal cancer after preoperative CRT may be safe and feasible if performed by a highly skilled laparoscopic surgeon. Randomized controlled trials and long-term follow-up studies are necessary to support our results.
목차
Abstract
INTRODUCTION
METHODS
RESULTS
DISCUSSION
CONFLICTS OF INTEREST
REFERENCES
참고문헌 (26)
참고문헌 신청
1. [학술지(정기간행물)] - Nelson H / 2004 / A comparison of laparoscopically assisted and open colectomy for colon cancer / N Engl J Med 350 : 2050 ~ 2059
2. [학술지(정기간행물)] - Colon Cancer Laparoscopic or Open Resection Study Group / 2009 / Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial / Lancet Oncol 10 : 44 ~ 52
3. [학술지(정기간행물)] - Lacy AM / 2002 / Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial / Lancet 359 : 2224 ~ 2229
4. [학술지(정기간행물)] - Leung KL / 2004 / Laparoscopic resection of rectosigmoid carcinoma: prospective randomised trial / Lancet 363 : 1187 ~ 1192
5. [학술지(정기간행물)] - Jayne DG / 2007 / Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group / J Clin Oncol 25 : 3061 ~ 3068
2. [학술지(정기간행물)] - Colon Cancer Laparoscopic or Open Resection Study Group / 2009 / Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial / Lancet Oncol 10 : 44 ~ 52
3. [학술지(정기간행물)] - Lacy AM / 2002 / Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial / Lancet 359 : 2224 ~ 2229
4. [학술지(정기간행물)] - Leung KL / 2004 / Laparoscopic resection of rectosigmoid carcinoma: prospective randomised trial / Lancet 363 : 1187 ~ 1192
5. [학술지(정기간행물)] - Jayne DG / 2007 / Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group / J Clin Oncol 25 : 3061 ~ 3068
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UCI(KEPA) : I410-ECN-0101-2014-514-000804357