Extent of resection for T2N0 gallbladder carcinoma regarding concurrent extrahepatic bile duct resection

Sung-Chan Gwark; Shin Hwang; Ki-Hun Kim; Yong-Joo Lee; Kwang-Min Park; Chul-Soo Ahn; Deok-Bog Moon; Tae-Yong Ha; Gi-Won Song; Dong-Hwan Jung; Gil-Chun Park; Sung-Gyu Lee

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자료유형: 학술저널

저자정보: Sung-Chan Gwark (University of Ulsan College of Medicine) Shin Hwang (University of Ulsan College of Medicine) Ki-Hun Kim (University of Ulsan College of Medicine) Yong-Joo Lee (University of Ulsan College of Medicine) Kwang-Min Park (University of Ulsan College of Medicine) Chul-Soo Ahn (University of Ulsan College of Medicine) Deok-Bog Moon (University of Ulsan College of Medicine) Tae-Yong Ha (University of Ulsan College of Medicine) Gi-Won Song (University of Ulsan College of Medicine) Dong-Hwan Jung (University of Ulsan College of Medicine) Gil-Chun Park (University of Ulsan College of Medicine) Sung-Gyu Lee (University of Ulsan College of Medicine)

저널정보: 한국간담췌외과학회 Annals of Hepato-Biliary-Pancreatic Surgery 한국간담췌외과학회지 제16권 제4호

발행연도: 2012.12

수록면: 142 - 146 (5page)

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Backgrounds/Aims: Gallbladder carcinoma (GBCa) T2 lesions are considered to be advanced tumors showing diverse features in tumor extent. When this T2 lesion does not involve the cystic duct and there is no evidence of lymph node metastasis, we have to consider what is the most reasonable extent of resection - that is, whether to perform concurrent extra-hepatic bile duct resection (EHBD) resection or not. This study intends to evaluate the adequacy of EHBD resection in patients undergoing resection for T2N0 GBCa. Methods: From our institutional database of GBCa, 48 cases of T2N0 GBCa who underwent R0 resection during November 1995 and August 2008 were selected. Patients who underwent prior laparoscopic cholecystectomy were excluded. Their medical records were reviewed retrospectively. Results: Their mean age was 63.2±83.3 years and females were 25. The mean serum CA19-9 level was 37.3±89.3 ng/ml. The extents of liver resection were wedge resection (n=36) and segment 4a+5 resection (n=12). Concurrent EHBD resection was performed in 16 (33.3%) patients. No fatal surgical complication occurred. The majority of tumor pathology was adenocarcinoma (n=42), with additional unusual types as papillary (n=3), saromatoid (n=1), signet ring cell (n=1) and adenosquamous (n=1) cancers. The overall survival rate was 87.1% at 1 year, 69.5% at 3 years and 61.7% at 5 years. After exclusion of mortalities not related to cancer, the overall patient survival rate was 89.6% at 1 year, 72.9% at 3 years and 64.7% at 5 years, with 3-year survival rates of 72% in the EHBD resection group and 69.2% in the non-resection group (p=0.661). Conclusions: The results of this study indicate that concurrent EHBD resection did not improve patient survival when R0 resection was achieved in patients with T2N0 GBCa. Therefore, routine EHBD resection may not be indicated for T2N0 GBCa unless the tumor is close to the cystic duct. (Korean J Hepatobiliary Pancreat Surg 2012;16:142-146)

#Gallbladder carcinoma #Extrahepatic bile duct resection #Extended cholecystectomy #Recurrence

참고문헌 (27)

참고문헌 신청

1. [학술지(정기간행물)] - Kohya N / 2008 / Hepatectomy of segment 4a and 5 combined with extra-hepatic bile duct resection for T2 and T3 gallbladder carcinoma / J Surg Oncol 97 : 498 ~ 502

2. [학술대회논문] - Nimura Y / 2002 / Extended surgery in bilio-pancreatic cancer: the Japanese experience / Semin Oncol 29 (6 Suppl 20) : 17 ~ 22

3. [학술지(정기간행물)] - Tsukada K / 1996 / Outcome of radical surgery for carcinoma of the gallbladder according to the TNM stage / Surgery 120 : 816 ~ 821

4. [학술지(정기간행물)] - Wakai T / 2001 / Early gallbladder carcinoma does not warrant radical resection / Br J Surg 88 : 675 ~ 678

5. [학술지(정기간행물)] - Shimizu Y / 2004 / Should the extrahepatic bile duct be resected for locally advanced gallbladder cancer? / Surgery 136 : 1012 ~ 1017