Effect of early enteral nutrition after hepatectomy in hepatocellular carcinoma patients

Jonghwan Lee; Choon Hyuck David Kwon; Jong Man Kim; Milljae Shin; Jae-Won Joh

추천

검색

질문

자료유형: 학술저널

저자정보: Jonghwan Lee (Sungkyunkwan University School of Medicine) Choon Hyuck David Kwon (Sungkyunkwan University School of Medicine) Jong Man Kim (Sungkyunkwan University School of Medicine) Milljae Shin (Sungkyunkwan University School of Medicine) Jae-Won Joh (Sungkyunkwan University School of Medicine)

저널정보: 한국간담췌외과학회 Annals of Hepato-Biliary-Pancreatic Surgery 한국간담췌외과학회지 제16권 제4호

발행연도: 2012.12

수록면: 129 - 133 (5page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Backgrounds/Aims: To evaluate the effect of early enteral nutrition after hepatectomy in hepatocellular carcinoma (HCC) patients on postoperative gastrointestinal motility recovery and admission days, liver function and nutrition recovery, and postoperative complication. Methods: From August 2010 to July 2011, 102 patients with primary HCC underwent hepatectomy. Forty two patients took a sip of water (SOW) at postoperative day (POD)#1, soft blended diet (SBD) at POD#2 (early diet group, ED group), otherwise 60 patients took a SOW at POD#3, SBD at POD#4 (conventional diet group, CD group). Postoperative flatus-pass day, stool-pass day, nausea, vomiting, admission days, immediate postoperative (POD#0) and POD#1, 3, 5, 7 profiles of albumin, prothrombin time (PT) INR, total bilirubin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), white blood cell (WBC), and POD#1, 3, 5, 7 profiles of C-reactive protein (CRP), and postoperative complications cases were compared between ED group and CD group. All clinical data were compared retrospectively. Results: Flatus-pass days (p＜0.01), stool-pass days (p＜0.01) and postoperative admission days (p=0.012) were shorter in ED group. Total bilirubin levels were higher at POD#0, 1, 3 but lower or similar at POD#5, 7 in ED group. AST, ALT levels were higher at POD#0 but lower at POD#1, 3, 5. There were no significant differences in albumin, PT INR, WBC, CRP and postoperative complication rates. Conclusions: ED group had no difference in nutritional recovery and postoperative complication rates compared to CD group but it has better gastrointestinal motility recovery, liver function recovery, and shorter postoperative admission days. (Korean J Hepatobiliary Pancreat Surg 2012;16:129-133)

#Early recovery after surgery #Early diet #Gastrointestinal motility #Liver function #Postoperative admission days

참고문헌 (10)

참고문헌 신청

1. [학술지(정기간행물)] - Barbiroli B / 1971 / DNA synthesis and interaction between controlled feeding schedules and partial hepatectomy in rats / Science 172 : 738 ~ 741

2. [학술지(정기간행물)] - Kirsch RE / 1979 / The effect of intragastric feeding with amino acids on liver regeneration after partial hepatectomy in the rat / Am J Clin Nutr 32 : 738 ~ 740

3. [학술지(정기간행물)] - Kallenbach M / 1983 / Kinetics of DNA synthesis in feeding-dependent and independent hepatocyte populations of rats after partial hepatectomy / Cell Tissue Kinet 16 : 321 ~ 332

4. [학술지(정기간행물)] - Torosian MH / 1999 / Perioperative nutrition support for patients undergoing gastrointestinal surgery: critical analysis and recommendations / World J Surg 23 : 565 ~ 569

5. [학술지(정기간행물)] - Fan ST / 1994 / Perioperative nutritional support in patients undergoing hepatectomy for hepatocellular carcinoma / N Engl J Med 331 : 1547 ~ 1552