지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.10
- 수록면
- 389 - 395 (7page)
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초록· 키워드
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The study elucidated carbohydrase inhibition, anti-cancerous, free radical scavenging properties and also investigated the DNA and protein protection abilities of methanolic root extract of Rumex crispus (RERC). For this purpose, pulverized roots of Rumex crispus was extracted in methanol (80% and absolute conc.) for 3 hrs for 60℃ and filtered and evaporated with vacuum rotary evaporator. RERC showed high phenolic content (211 ㎍/GAE equivalent) and strong 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging (IC<SUB>50</SUB> = 42.86 (absolute methanol) and 36.91 ㎍/mL (80% methanolic extract)) and reduced power ability. Furthermore, RERC exhibited significant protective ability in H₂O₂/Fe<SUP>3+</SUP>/ascorbic acid-induced protein or DNA damage and percentage inhibition of the HT-29 cell growth rate following 80% methanolic RERC exposure at 400 ㎍/mL was observed to be highest (10.2%± 1.03). Moreover, methanolic RERC inhibited α-glucosidase and amylase effectively and significantly (P ＜ 0.05). Conclusively, RERC could be considered as potent carbohydrase inhibitor, anti-cancerous and anti-oxidant.
목차
Abstract
Introduction
Materials and Methods
Results
Discussion
References
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UCI(KEPA) : I410-ECN-0101-2014-594-001066099