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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.12
- 수록면
- 258 - 262 (5page)
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Purpose: Hepatic resection has been proven to be an effective therapy for metastatic colorectal carcinoma and it is a beneficial therapy for metastatic neuroendocrine tumors. Yet the role and efficacy of hepatic resection for metastatic noncolorectal nonneuroendocrine (NCNN) carcinoma have not yet been well defined. We evaluated the outcome and the prognostic factors of patients who are undergoing hepatic resection for metastases from NCNN carcinoma. Materials and
Methods: The records of 46 patients who underwent liver resection for NCNN metastasis from Oct. 1992 to May 2006 were analyzed. Among the 46 patients, 26 patients were excluded due to direct hepatic invasion from stomach cancer. The patient demographics, tumor characteristics, the treatment and the postoperative survival rate were analyzed.
Results: The median patient age was 54.9 years (range: 36-69 years) and there were 13 men (85.7%) and 7 women (15.3%). The mean survival time from the date of liver resection was 48±7.85 months, and the 5-year survival rate was 33.7%. The primary tumor sites were identified as gastrointestinal in 60% of the patients and non-gastrointestinal in 40% of the patients. Patients with a gastrointestinal primary tumor had a median survival time that was similar to that of patients with non-gastrointestinal primary tumor (48 months versus 42 months, respectively, p=0.847). The number of liver metastases was an independent prognostic factor (p=0.030).
Conclusions: In selected patients with NCNN liver metastasis, hepatic resection is an effective management and it can also prolong survival. Hepatic resection should be considered if lymphatic invasion and metastasis of the other organ are excluded.
Methods: The records of 46 patients who underwent liver resection for NCNN metastasis from Oct. 1992 to May 2006 were analyzed. Among the 46 patients, 26 patients were excluded due to direct hepatic invasion from stomach cancer. The patient demographics, tumor characteristics, the treatment and the postoperative survival rate were analyzed.
Results: The median patient age was 54.9 years (range: 36-69 years) and there were 13 men (85.7%) and 7 women (15.3%). The mean survival time from the date of liver resection was 48±7.85 months, and the 5-year survival rate was 33.7%. The primary tumor sites were identified as gastrointestinal in 60% of the patients and non-gastrointestinal in 40% of the patients. Patients with a gastrointestinal primary tumor had a median survival time that was similar to that of patients with non-gastrointestinal primary tumor (48 months versus 42 months, respectively, p=0.847). The number of liver metastases was an independent prognostic factor (p=0.030).
Conclusions: In selected patients with NCNN liver metastasis, hepatic resection is an effective management and it can also prolong survival. Hepatic resection should be considered if lymphatic invasion and metastasis of the other organ are excluded.
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참고문헌 (17)
참고문헌 신청
1. [학술지(정기간행물)] - Srinevas KR / 2007 / Resection of noncolorectal nonneuroendocrine liver metastases : A comparative analysis / J Am Coll Surg 204 : 372 ~ 382
2. [학술지(정기간행물)] - Earle SA / 2006 / Hepatectomy enables prolonged survival in select patients with isolated noncolorectal liver metastasis / J Am Coll surg 203 : 436 ~ 446
3. [학술지(정기간행물)] - Schlag P / 1990 / Resection of liver metastases in colorectal cancer-competitive analysis of treatment results in synchronous versus metachronous metastases / Eur J Surg Oncol 16 : 360 ~ 365
4. [학술지(정기간행물)] - Dominique E / 1998 / Resection of liver metastases from a noncolorectal primary: indications and results based on 147 monocentric patients / J Am Coll Surg 187 : 487 ~ 493
5. [학술지(정기간행물)] - Schwartz SI / 1995 / Hepatic resection for noncolorectal nonneuroendocrine metastases / World J Surg 19 : 72 ~ 75
2. [학술지(정기간행물)] - Earle SA / 2006 / Hepatectomy enables prolonged survival in select patients with isolated noncolorectal liver metastasis / J Am Coll surg 203 : 436 ~ 446
3. [학술지(정기간행물)] - Schlag P / 1990 / Resection of liver metastases in colorectal cancer-competitive analysis of treatment results in synchronous versus metachronous metastases / Eur J Surg Oncol 16 : 360 ~ 365
4. [학술지(정기간행물)] - Dominique E / 1998 / Resection of liver metastases from a noncolorectal primary: indications and results based on 147 monocentric patients / J Am Coll Surg 187 : 487 ~ 493
5. [학술지(정기간행물)] - Schwartz SI / 1995 / Hepatic resection for noncolorectal nonneuroendocrine metastases / World J Surg 19 : 72 ~ 75
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UCI(KEPA) : I410-ECN-0101-2014-514-001253945