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논문 기본 정보

자료유형
학술저널
저자정보
Jae Myeong Lee (Ajou University School of Medicine) Young Joo Lee (University of Ulsan College of Medicine) Chan Wook Kim (University of Ulsan College of Medicine) Ki Miung Moon (University of Ulsan College of Medicine) Myung Wook Kim (Ajou University School of Medicine)
저널정보
한국간담췌외과학회 Annals of Hepato-Biliary-Pancreatic Surgery 한국간담췌외과학회지 제13권 제2호
발행연도
2009.6
수록면
103 - 108 (6page)

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Introduction: Biliary drainage is tried before surgery because it is thought that obstructive jaundice is associated with post-operative mortality and morbidity. However, there are no confirmed criteria about the optimal operation time after drainage. We attempted to determine the appropriate pre-operative bilirubin level after drainage which should be achieved before pancreaticoduodenectomy is done for extrahepatic bile duct cancer.
Methods: We reviewed 100 patients (69 males and 31 females with a mean age of 61.3 ± 9.4 years) who underwent pancreaticoduodenectomy after a pre-operative biliary drainage procedure for distal common bile duct cancer by one surgeon at the Asan Medical Center in Seoul Korea between 1994 and 2005.
Results: We compared the group with pre-operative bilirubin levels < 5.0 mg/dl (N = 14) with the group with a bilirubin levels ≥ 5.0 mg/dl (N = 86). In the bilirubin < 5.0 group, the preoperative hemoglobin level was lower (p = 0.001), the pre-operative creatinine level was higher (p = 0.000), pre-operative cholangitis was more frequent (p = 0.034), and the bilirubin level at the time of admission was also higher (p = 0.000). The bilirubin < 5.0 group showed no postoperative morbidity, while there was a 25.6% morbidity rate in the bilirubin ≥ 5.0 group (p = 0.032).
Conclusion: The pre-operative bilirubin < 5.0 and ≥ 5.0 groups had a clear difference in postoperative morbidity. Therefore, we suggest waiting until the pre-operative bilirubin level decreases to < 5.0 mg/dl after biliary drainage.

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Introduction
Methods
Results
Discussion
Conclusion
References

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UCI(KEPA) : I410-ECN-0101-2014-514-001253687