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자료유형
학술저널
저자정보
Sung Ha Lee (Chonbuk National University Medical School and Hospital) Jae Do Yang (Chonbuk National University Medical School and Hospital) Hong Pil Hwang (Chonbuk National University Medical School and Hospital) Hee Chul Yu (Chonbuk National University Medical School and Hospital) Baik Hwan Cho (Chonbuk National University Medical School and Hospital)
저널정보
한국간담췌외과학회 Annals of Hepato-Biliary-Pancreatic Surgery 한국간담췌외과학회지 제16권 제2호
발행연도
2012.6
수록면
59 - 64 (6page)

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Backgrounds/Aims: The aim of this study is to analyze surgical outcomes and prognostic factors affecting survival after surgical resection in patients with gallbladder cancer. Methods: We retrospectively reviewed 86 patients treated surgically for gallbladder cancer from January 2000 to December 2009 at Chonbuk National University Hospital. Clinicopathologic factors, surgical treatment and outcome data were analyzed. Results: Among the 86 patients (44 male, 42 female) with gallbladder cancer, the mean age was 62.9 years (range: 32-80) and the median survival was 42.4±3.5 month. The overall cumulative survival rates of 86 patients were for 1 year, 83.7%; 3 year, 67.4%; 5 year survival, 61.7%. Univariate analysis revealed that preoperative serum alanine aminotransferase, alkaline phosphatase, total bilirubin, carcinoembryonic antigen (CEA), T staging, N staging were statistically significantly associated with survival. CEA (p=0.004) and T staging (p=0.005) were associated with survival in multivariate analysis. Two-year survival rates were analyzed according to the methods of surgical resection, with simple cholecystectomy showing 100%, whereas extended cholecystectomy showed about 83% in T1b. We could not find out any adverse effect of the simple cholecystectomy for survival. Conclusions: CEA and T stage are independent significant prognostic factor associated with patient survival in our study. Simple cholecystectomy can be regarded as curative resection in stage T1b. Longer observation periods and more cases will be needed to confirm these conclusions. (Korean J Hepatobiliary Pancreat Surg 2012;16:59-64)

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UCI(KEPA) : I410-ECN-0101-2014-514-001272606