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논문 기본 정보

자료유형
학술저널
저자정보
Song Soo Yang (University of Ulsan) Chang Sik Yu (University of Ulsan) Yong Sik Yoon (University of Ulsan) Sang Nam Yoon (University of Ulsan) Seok-Byung Lim (University of Ulsan) Jin Cheon Kim (University of Ulsan)
저널정보
대한외과학회 Annals of Surgical Treatment and Research Journal of the Korean Surgical Society Vol.83 No.3
발행연도
2012.9
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141 - 148 (8page)

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초록· 키워드

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Purpose: To assess the incidence and factors predictive of early postoperative complications in Korean patients who undergo surgery for Crohn’s disease (CD). Methods: We retrospectively assessed 350 patients (246 males, 104 females; mean age, 30 ±9 years) who underwent surgery for primary or recurrent CD at Asan Medical Center between January 1991 and May 2010. The incidence and predictive factors of early postoperative complications were analyzed by both univariate and multivariate analyses. Results: Of the 350 patients, 81 patients (23.1%) developed postoperative complications, the most common being septic complications (54 patients), including 19 cases of wound infection. Thirty patients (8.6%) required re-operations, and only one patient died. Multivariate analysis showed that four factors were independently associated with a high risk of early postoperative complications; preoperative moderate to severe anemia (hematocrit concentration <30%; odds ratio [OR], 3.1 ; 95% confidence interval [CI], 1.6 to 5.9), hypoalbuminemia (serum albumin level <3.0 g/dL; OR, 2.6; 95% CI, 1.4 to 4.7), emergency surgery (OR, 4.0; 95% CI, 1.5 to 10.6), and covering stoma (OR, 2.6; 95% CI, 1.3 to 5.4). Correction of preoperative moderate to severe anemia and hypoalbuminemia decreased the incidence of postoperative complications. Mean hospital stay was significantly longer in patients with than without postoperative complications (31.3 ± 27.2 days vs. 10.3 ± 3.8 days, P <0.001). Conclusion: Preoperative anemia, low albumin level, emergency surgery, and covering stoma significantly increased the risk of early postoperative complications in patients with CD. Correcting preoperatively deficient nutritional factors may reduce postoperative morbidities.

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UCI(KEPA) : I410-ECN-0101-2014-514-001420266