지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Journal of the Korean Surgical Society Vol.83 No.4
- 발행연도
- 2012.10
- 수록면
- 237 - 241 (5page)
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초록· 키워드
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Purpose: Accurate diagnosis and optimal management of acute appendicitis, despite being the most common surgical emergency encountered in emergency departments, is often delayed in pediatric patients due to nonspecific symptoms and communication barriers, often leading to more complicated cases. The aim of this study is to investigate the diagnostic significance of common laboratory markers. Methods: A total of 421 patients aged 15 and younger underwent surgical treatment for acute appendicitis. We conducted a retrospective analysis for white blood cell (WBC), C-reactive protein (CRP) and bilirubin. All patients were classified into simple or complicated appendicitis groups based on postoperative histology. Results: The mean age of the patients in the complicated appendicitis group was younger than that in the simple group (P = 0.005). WBC, CRP and bilirubin levels were significantly higher in the complicated appendicitis group (P ＜ 0.001, ＜0.001, 0.002). The relative risk for complicated appendicitis was calculated using age, WBC, CRP and bilirubin. Elevated CRP levels were associated with the highest risk for complicated appendicitis (hazard ratio [HR], 2.53; 95% confidence interval [CI], 1.38 to 4.65) followed by WBC (HR, 2.42; 95% CI, 1.07 to 5.46) and bilirubin (HR, 2.04; 95% CI, 1.09 to 3.82). The most sensitive markers for diagnosing complicated appendicitis were WBC (95.2%) and CRP (86.3%). Bilirubin levels showed the highest specificity at 74.8%. Conclusion: The risk of complicated appendicitis was significantly higher in patients younger than 10 years old. Preoperative WBC, CRP and bilirubin have clinical value in diagnosing complicated appendicitis with a HR of 2.0 to 2.5. Our results suggest that the utilization of WBC, CRP, and bilirubin can assist in the diagnosis of complicated appendicitis in pediatric patients, allowing prompt diagnosis and optimal management.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
CONFLICTS OF INTEREST
REFERENCES
참고문헌 (16)
참고문헌 신청
1. [학술지(정기간행물)] - Pearl RH / 1995 / Pediatric appendectomy / J Pediatr Surg 30 : 173 ~ 178
3. [학술지(정기간행물)] - Mueller BA / 1986 / Appendectomy and the risk of tubal infertility / N Engl J Med 315 : 1506 ~ 1508
4. [학술지(정기간행물)] - Pena BM / 2002 / Effect of an imaging protocol on clinical outcomes among pediatric patients with appendicitis / Pediatrics 110 : 1088 ~ 1093
5. [학술지(정기간행물)] - Brenner DJ / 2002 / Estimating cancer risks from pediatric CT: going from the qualitative to the quantitative / Pediatr Radiol 32 : 228 ~ 231
6. [학술지(정기간행물)] - Doria AS / 2006 / US or CT for diagnosis of appendicitis in children and adults? A meta-analysis / Radiology 241 : 83 ~ 94
3. [학술지(정기간행물)] - Mueller BA / 1986 / Appendectomy and the risk of tubal infertility / N Engl J Med 315 : 1506 ~ 1508
4. [학술지(정기간행물)] - Pena BM / 2002 / Effect of an imaging protocol on clinical outcomes among pediatric patients with appendicitis / Pediatrics 110 : 1088 ~ 1093
5. [학술지(정기간행물)] - Brenner DJ / 2002 / Estimating cancer risks from pediatric CT: going from the qualitative to the quantitative / Pediatr Radiol 32 : 228 ~ 231
6. [학술지(정기간행물)] - Doria AS / 2006 / US or CT for diagnosis of appendicitis in children and adults? A meta-analysis / Radiology 241 : 83 ~ 94
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UCI(KEPA) : I410-ECN-0101-2014-514-001420100