지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.8
- 수록면
- 494 - 504 (11page)
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초록· 키워드
오류제보하기
Osseointegration is a result of bone formation and bone regeneration, which place as the interface between bone and implant and biologic determinants such as cytokine, growth factors, bone matrix proteins play an important role in osseointegration. The purpose of this study is to compare the expression of TGF-β, IGF-I, BMP2, BMP4 during osseointegration.
We designed an experimental group which was inserted with a RBM surface titanium implants and machined surface, and compared with a control group which had a simple bone cavity and normal bone. Titanium implants were placed into tibia of 8 rabbits. We compared the expression of TGF-β, IGF-1, BMP2, BMP4 using RT-PCR (reverse transcriptase chain reaction) analysis in day 3, 7, 14 and 28 of implant insertion.
According to the results, growth factors of experimental groups were more expressed than control groups. Among experimental groups, expression of TGF-β, IGF-1, BMP-4 of RBM group had tendency to increase more at 14th, 28th days than Machined surface group.
Therefore, our results suggest that TGF-β, IGF-1, BMP4 are expressed within the bone around the implant and more increased around rough surface implants while osseointegration occurs after dental implant insertion.
We designed an experimental group which was inserted with a RBM surface titanium implants and machined surface, and compared with a control group which had a simple bone cavity and normal bone. Titanium implants were placed into tibia of 8 rabbits. We compared the expression of TGF-β, IGF-1, BMP2, BMP4 using RT-PCR (reverse transcriptase chain reaction) analysis in day 3, 7, 14 and 28 of implant insertion.
According to the results, growth factors of experimental groups were more expressed than control groups. Among experimental groups, expression of TGF-β, IGF-1, BMP-4 of RBM group had tendency to increase more at 14th, 28th days than Machined surface group.
Therefore, our results suggest that TGF-β, IGF-1, BMP4 are expressed within the bone around the implant and more increased around rough surface implants while osseointegration occurs after dental implant insertion.
목차
ABSTRACT
서론
연구 재료 및 방법
연구성적 및 결과
총괄 및 고찰
결론
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UCI(KEPA) : I410-ECN-0101-2013-515-003365096