Behavioral characteristics of prism adaptation have received extensive research interests for the last few decades, and the recent emergence of the cognitive neuroscience has started to unveil the neural correlates of this process. However, the underlying mechanisms facilitating such sensory-motor realignment process isn’t clear. Purpose of this study was to examine the role of proprioceptive suppression as one of the driving mechanisms for the prism adaptation. Single pulse transcranial magnetic stimulation (TMS) when applied to the somatosensory cortex can simulate the proprioceptive suppression. If this suppression is a part of the adaptation process, the changes in the adaptation pattern can be hypothesized if the TMS introduced this in an artificial manner. As a result, the amounts of changes in total (total shift) and proprioceptive (proprioceptive shift) perceptions did not displayed the influence of the TMS upon completion of the prism adaptation process. However, further investigation reveal the effect of the TMS during the prism-on period. The rate of adaptation and the amount of trial-to-trial adjustments significantly increased when the stimulation was applied during the initial phase of the reaching movement. While the effect of TMS successfully facilitate the adaptation process during the prism on trials, the performance seems to experience the saturation effects so that the benefit of the proprioceptive suppression may not be reflected to the post-prism performance. In conclusion, the influence of the proprioceptive suppression during the prism adaptation process has been confirmed.