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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.6
- 수록면
- 137 - 140 (4page)
이용수
이 논문의 연구 히스토리 (2)
2012
Anti-inflammatory effects of Houttuynia cordata supercritical extract in carrageenan-air pouch inflammation models
Dajeong Kim
,
Dongsun Pa
,
k
외 4명
한국실험동물학회 학술발표대회 논문집
2012.08
학술대회자료
Anti-inflammatory effects of Houttuynia cordata supercritical extract in carrageenan-air pouch inflammation model
Dajeong Kim
,
Dongsun Pa
,
k
외 7명
Laboratory Animal Research
2012.06
학술저널
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초록· 키워드
오류제보하기
Anti-inflammatory effects of Houttuynia cordata supercritical extract (HSE) were investigated in rat carrageenan-air pouch model. Oral administration of HSE (50-200 ㎎/㎏) suppressed carrageenaninduced exudation and albumin leakage, as well as inflammatory cell infiltration at a high dose (200 ㎎/㎏). Intraperitoneal injection of dexamethasone (2 ㎎/㎏) only decreased exudation and cell infiltration, while indomethacin (2 ㎎/㎏, i.p.) reduced exudate volume and albumin content without influence on the cell number. HSE lowered tumor-necrosis factor-α (TNF-α) and nitric oxide (NO), as well as prostaglandin E2 (PGE2). Dexamethasone only reduced TNF-α and NO, while indomethacin decreased PGE2. The results indicate that HSE exhibits anti-inflammatory effects by inhibiting both TNF-α-NO and cyclooxygenase-2-PGE2 pathways.
목차
등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
1. [학술지(정기간행물)] - Hayashi K / 1995 / Virucidal effects of the steam distillate from Houttuynia cordata and its components on HSV-1, influenza virus, and HIV / Planta Med 61 (3) : 237 ~ 241
2. [학술지(정기간행물)] - Lu H / 2006 / Variation in chemical composition and antibacterial activities of essential oils from two species of Houttuynia THUNB / Chem Pharm Bull (Tokyo) 54 (7) : 936 ~ 940
3. [학술지(정기간행물)] - Lee JS / 2008 / Suppressive effects of Houttuynia cordata Thunb (Saururaceae) extract on Th2 immune response / J Ethnopharmacol 117 (1) : 34 ~ 40
4. [학술지(정기간행물)] - Li GZ / 2005 / Inhibitory effects of Houttuynia cordata water extracts on anaphylactic reaction and mast cell activation / Biol Pharm Bull 28 (10) : 1864 ~ 1868
5. [학술지(정기간행물)] - Chen YY / 2003 / A study of the antioxidative and antimutagenic effects of Houttuynia cordata Thunb. using an oxidized frying oil-fed model / J Nutr Sci Vitaminol (Tokyo) 49 (5) : 327 ~ 333
2. [학술지(정기간행물)] - Lu H / 2006 / Variation in chemical composition and antibacterial activities of essential oils from two species of Houttuynia THUNB / Chem Pharm Bull (Tokyo) 54 (7) : 936 ~ 940
3. [학술지(정기간행물)] - Lee JS / 2008 / Suppressive effects of Houttuynia cordata Thunb (Saururaceae) extract on Th2 immune response / J Ethnopharmacol 117 (1) : 34 ~ 40
4. [학술지(정기간행물)] - Li GZ / 2005 / Inhibitory effects of Houttuynia cordata water extracts on anaphylactic reaction and mast cell activation / Biol Pharm Bull 28 (10) : 1864 ~ 1868
5. [학술지(정기간행물)] - Chen YY / 2003 / A study of the antioxidative and antimutagenic effects of Houttuynia cordata Thunb. using an oxidized frying oil-fed model / J Nutr Sci Vitaminol (Tokyo) 49 (5) : 327 ~ 333
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UCI(KEPA) : I410-ECN-0101-2013-510-002637176