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논문 기본 정보

자료유형
학술저널
저자정보
Kyu Chul Kang (인하대학교) Seok Hwan Shin (인하대학교) Yeon Ji Lee (인하대학교) Yoon Seok Heo (인하대학교)
저널정보
대한외과학회 Annals of Surgical Treatment and Research 대한외과학회지 Vol.82 No.6
발행연도
2012.6
수록면
347 - 355 (9page)

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초록· 키워드

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Purpose: The impressive effect of LRYGBP on mildly obese patients (30 ㎏/㎡ < BMI < 35 ㎏/㎡) with T2DM raises the argument for lowering the threshold for surgical intervention to non-obesity (BMI < 30 ㎏/㎡). The goal of this study was to evaluate the effect of gastrectomy on non-obese patients with T2DM and what preoperative clinical factors are associated with postoperative long term improvement. Methods: In this retrospective review, we analyzed the change in diabetic status in 75 patients with gastric cancer undergoing three different gastrectomies in a single institution from June 1996 to September 2009. Pre- and postoperative fasting blood glucose, serum hemoglobin A1c and diabetic medication requirements were compared. The demographic data and other biochemical markers were also collected. Results: At an average follow-up of 35.0 ± 25.9 months, we collected the data of 75 patients and evaluated the change of diabetes status. There was no resolution of diabetes in Billroth-Ⅰ (B-Ⅰ) group, and 45.2% of patients improved whereas the resolution rate of Billroth-Ⅱ (B-Ⅱ) and RY group was 22.2% and 23.5% and 85.2% and 88.2%, respectively. The improvement rate of diabetes mellitus (DM) status was 7.46 times higher in B-Ⅱ than in B-Ⅰ patients. The method of reconstruction is the most powerful factor and severity and duration of diabetes showed significant clinical factors for the improvement of the disease after surgery. Conclusion: According to these results, foregut-bypass procedure may improve the type 2 DM better than can be explained by the effect of weight loss only. Diabetes remission is significantly higher in those with duration of diabetes less than 5 years.

목차

INTRODUCTION
METHODS
RESULTS
DISCUSSION
CONFLICTS OF INTEREST
REFERENCES

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UCI(KEPA) : I410-ECN-0101-2013-514-002669245