지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.9
- 수록면
- 187 - 194 (8page)
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초록· 키워드
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Purpose: Attempt to identify the beneficial effects associated with surgical procedures on survival outcome of patients with recurrent cholangiocarcinoma. Methods: 921 patients diagnosed with cholangiocarcinoma underwent surgical resection with curative intent in a single institute during the last 15 years. Patients with recurrent disease were divided into two groups according to whether surgical procedures were performed for the treatment of recurrence. Clinicopathologic variables, ranges of survival based on sites of recurrence, and types of treatment were analyzed retrospectively. Results: The median follow- up period was 21.8 months and 316 (34.3%) patients had recurrence. 27 (group A) patients with recurrent disease were treated surgically and 289 patients (group B) were not treated. Liver resection, metastasectomy, pancreaticoduodenectomy, partial pancreatectomy, and regional lymph node dissection were performed on the patients in group A. The overall survival rate was statistically higher in group A (P = 0.001). Among the surgical procedures, resection of locoregional recurrences (except liver) in abdominal cavity (4.0 to 101.8 months vs. 0.6 to 71.6 months) and metastasectomy of abdominal or chest wall (3.5 to 18.9 months vs. 1.9 to 2.2 months) showed remarkable differences with respect to the range of survival. Conclusion: Better survival outcomes can be expected by performing surgical resection of locoregional recurrences (except liver) in abdominal cavity and abdominal or chest wall metastatic lesions in recurrent cholangiocarcinoma.
목차
Purpose
INTRODUCTION
METHODS
RESULTS
DISCUSSION
CONFLICTS OF INTEREST
REFERENCES
참고문헌 (28)
참고문헌 신청
1. [학술지(정기간행물)] - Kwon OS / 2007 / Distant skeletal muscle metastasis from intrahepatic cholangiocarcinoma presenting as Budd-Chiari syndrome / WORLD JOURNAL OF GASTROENTEROLOGY 13 : 3141 ~ 3143
2. [학술지(정기간행물)] - Tao LY / 2010 / Risk factors for intrahepatic and extrahepatic cholangiocarcinoma: a case-control study in China / Liver Int 30 : 215 ~ 221
3. [학술지(정기간행물)] - 박세경 / 2010 / Detection of distant metastasis to skeletal muscle by 18F-FDG-PET in a case of intrahepatic cholangiocarcinoma / Clinical and Molecular Hepatology 16 (3) : 325 ~ 328
4. [학술지(정기간행물)] - Zhang KJ / 2010 / The E-cadherin repressor slug and progression of human extrahepatic hilar cholangiocarcinoma / J Exp Clin Cancer Res 29 : 88 ~
5. [학술지(정기간행물)] - Ito Y / 2007 / Solitary recurrence of hilar cholangiocarcinoma in a mediastinal lymph node two years after curative resection / World J Gastroenterol 13 : 2243 ~ 2246
2. [학술지(정기간행물)] - Tao LY / 2010 / Risk factors for intrahepatic and extrahepatic cholangiocarcinoma: a case-control study in China / Liver Int 30 : 215 ~ 221
3. [학술지(정기간행물)] - 박세경 / 2010 / Detection of distant metastasis to skeletal muscle by 18F-FDG-PET in a case of intrahepatic cholangiocarcinoma / Clinical and Molecular Hepatology 16 (3) : 325 ~ 328
4. [학술지(정기간행물)] - Zhang KJ / 2010 / The E-cadherin repressor slug and progression of human extrahepatic hilar cholangiocarcinoma / J Exp Clin Cancer Res 29 : 88 ~
5. [학술지(정기간행물)] - Ito Y / 2007 / Solitary recurrence of hilar cholangiocarcinoma in a mediastinal lymph node two years after curative resection / World J Gastroenterol 13 : 2243 ~ 2246
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UCI(KEPA) : I410-ECN-0101-2013-514-002683845