지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.2
- 수록면
- 81 - 85 (5page)
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Purpose: This study was performed to evaluate the feasibility of the Gamma Knife Surgery on the symptomatic control of brain metastasis from breast carcinoma.
Methods: We retrospectively reviewed patients with brain metastases from breast cancer who underwent Gamma Knife Surgery at our hospital, between May 2004 and November 2007. Total 82 metastases were treated with 26 cycles of Leksell gamma knife. Freedom from local recurrence and survival time were analyzed by the Kaplan-Meier method.
Results: 17 patients with 82 metastases were treated over 26 Gamma Knife Surgery sessions. The mean time to brain metastases was 41.7 months (8∼84), median number was 2.0 (1∼10), and median volume was 7.4 ㎤ (0.6∼25.4). Radiologic response occurred in 84.6%, and the rate of symptom relief was 73.1%. Local brain tumor recurrences were observed in 15.3% and intracranial distant recurrence occurred in 57.7% that occurred within 3.2 months. The median length of survival for all patients was 9.3 months (95% confidence interval, 4.23∼9.37 months).
Conclusion: Gamma Knife Surgery is an effective and feasible treatment for symptomatic control of brain metastases from breast cancer patients who have severe extracranial metastases and short life expectancy.
Methods: We retrospectively reviewed patients with brain metastases from breast cancer who underwent Gamma Knife Surgery at our hospital, between May 2004 and November 2007. Total 82 metastases were treated with 26 cycles of Leksell gamma knife. Freedom from local recurrence and survival time were analyzed by the Kaplan-Meier method.
Results: 17 patients with 82 metastases were treated over 26 Gamma Knife Surgery sessions. The mean time to brain metastases was 41.7 months (8∼84), median number was 2.0 (1∼10), and median volume was 7.4 ㎤ (0.6∼25.4). Radiologic response occurred in 84.6%, and the rate of symptom relief was 73.1%. Local brain tumor recurrences were observed in 15.3% and intracranial distant recurrence occurred in 57.7% that occurred within 3.2 months. The median length of survival for all patients was 9.3 months (95% confidence interval, 4.23∼9.37 months).
Conclusion: Gamma Knife Surgery is an effective and feasible treatment for symptomatic control of brain metastases from breast cancer patients who have severe extracranial metastases and short life expectancy.
목차
서론
방법
결과
고찰
결론
REFERENCES
참고문헌 (21)
참고문헌 신청
1. [학술지(정기간행물)] - Kamby C / 1990 / The pattern of metastases in human breast cancer: methodological aspects and influence of prognostic factors / Cancer Treat Rev 17 : 37 ~ 61
2. [학술지(정기간행물)] - Tsukada Y / 1983 / Central nervous system metastasis from breast carcinoma. Autopsy study / Cancer 52 : 2349 ~ 2354
3. [단행본] - Posner JB / 1995 / Neurologic Complications of Cancer / F.A.Davis : 96 ~
4. [학술지(정기간행물)] - Gaspar LE / 2000 / Validation of the RTOG recursive partitioning analysis (RPA) classification for brain metastases / Int J Radiat Oncol Biol Phys 47 : 1001 ~ 1006
5. [학술지(정기간행물)] - Mahmoud-Ahmed AS / 2002 / Results of whole brain radiotherapy in patients with brain metastases from breast cancer: a retrospective study / Int J Radiat Oncol Biol Phys 54 : 810 ~ 817
2. [학술지(정기간행물)] - Tsukada Y / 1983 / Central nervous system metastasis from breast carcinoma. Autopsy study / Cancer 52 : 2349 ~ 2354
3. [단행본] - Posner JB / 1995 / Neurologic Complications of Cancer / F.A.Davis : 96 ~
4. [학술지(정기간행물)] - Gaspar LE / 2000 / Validation of the RTOG recursive partitioning analysis (RPA) classification for brain metastases / Int J Radiat Oncol Biol Phys 47 : 1001 ~ 1006
5. [학술지(정기간행물)] - Mahmoud-Ahmed AS / 2002 / Results of whole brain radiotherapy in patients with brain metastases from breast cancer: a retrospective study / Int J Radiat Oncol Biol Phys 54 : 810 ~ 817
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UCI(KEPA) : I410-ECN-0101-2013-514-002687974