지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.9
- 수록면
- 195 - 201 (7page)
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Purpose: We aimed to evaluate the early (＜30 days) results and to analyze risk factors for the development of stroke and new brain infarction (NBI) after carotid endarterectomy (CEA).
Methods: From September 2003 to August 2008, 233 CEAs were performed on 222 patients with critical internal carotid artery (ICA) stenosis in a single center. Patient characteristics, history of neurological symptoms, procedural details, and postoperative complications were examined based on the medical records. The incidence and risk factors for early postoperative stroke were evaluated. After excluding CEAs without performing diffusion-weighted brain MRI, 128 CEAs were investigated for frequency and the risk factors of NBI were analyzed. Chi-square test, Fisher’s exact test, Student T-test, and logistic regression model were used for statistical analysis.
Results: Of a total of 233 CEAs, any and ipsilateral stroke rates were 1.3% and 0.4%, respectively. There was no early postoperative mortality. Early postoperative complications included 4.3% in transient cranial nerve injury, 1.7% in myocardial infarction, and 3.4% in hematoma. In univariate analysis, the significant risk factor for stroke was plaque ulceration (P=0.04). The frequency of NBI and ipsilateral NBI were 8.4% and 3.1%, respectively. The ulceration on ipsilateral ICA revealed statistically significant risk factors for the development of NBI (RR, 5.29; 95% CI, 1.024∼27.325; P=0.04).
Conclusion: Our study showed a lower incidence of stroke and NBI after carotid endarterectomy and that it is safe procedure for the treatment of patients with severe (＞70%) carotid stenosis. We also found that plaque with ulceration was a significant risk factor for the development of postoperative NBI.
Methods: From September 2003 to August 2008, 233 CEAs were performed on 222 patients with critical internal carotid artery (ICA) stenosis in a single center. Patient characteristics, history of neurological symptoms, procedural details, and postoperative complications were examined based on the medical records. The incidence and risk factors for early postoperative stroke were evaluated. After excluding CEAs without performing diffusion-weighted brain MRI, 128 CEAs were investigated for frequency and the risk factors of NBI were analyzed. Chi-square test, Fisher’s exact test, Student T-test, and logistic regression model were used for statistical analysis.
Results: Of a total of 233 CEAs, any and ipsilateral stroke rates were 1.3% and 0.4%, respectively. There was no early postoperative mortality. Early postoperative complications included 4.3% in transient cranial nerve injury, 1.7% in myocardial infarction, and 3.4% in hematoma. In univariate analysis, the significant risk factor for stroke was plaque ulceration (P=0.04). The frequency of NBI and ipsilateral NBI were 8.4% and 3.1%, respectively. The ulceration on ipsilateral ICA revealed statistically significant risk factors for the development of NBI (RR, 5.29; 95% CI, 1.024∼27.325; P=0.04).
Conclusion: Our study showed a lower incidence of stroke and NBI after carotid endarterectomy and that it is safe procedure for the treatment of patients with severe (＞70%) carotid stenosis. We also found that plaque with ulceration was a significant risk factor for the development of postoperative NBI.
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REFERENCES
참고문헌 (23)
참고문헌 신청
1. [학술지(정기간행물)] - Murray CJ / 1997 / Mortality by cause for eight regions of the world: Global Burden of Disease Study / Lancet 349 : 1269 ~ 1276
2. [학술지(정기간행물)] - Thrift AG / 2001 / Incidence of the major stroke subtypes: initial findings from the North East Melbourne stroke incidence study (NEMESIS) / Stroke 32 : 1732 ~ 1738
3. [학술지(정기간행물)] - Chaturvedi S / 2005 / Carotid endarterectomy--an evidence-based review: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology / Neurology 65 : 794 ~ 801
4. [학술지(정기간행물)] - Eastcott HH / 1954 / Reconstruction of internal carotid artery in a patient with intermittent attacks of hemiplegia / Lancet 267 : 994 ~ 996
5. [학술지(정기간행물)] - Biller J / 1998 / Guidelines for carotid endarterectomy: a statement for healthcare professionals from a Special Writing Group of the Stroke Council, American Heart Association / Circulation 97 : 501 ~ 509
2. [학술지(정기간행물)] - Thrift AG / 2001 / Incidence of the major stroke subtypes: initial findings from the North East Melbourne stroke incidence study (NEMESIS) / Stroke 32 : 1732 ~ 1738
3. [학술지(정기간행물)] - Chaturvedi S / 2005 / Carotid endarterectomy--an evidence-based review: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology / Neurology 65 : 794 ~ 801
4. [학술지(정기간행물)] - Eastcott HH / 1954 / Reconstruction of internal carotid artery in a patient with intermittent attacks of hemiplegia / Lancet 267 : 994 ~ 996
5. [학술지(정기간행물)] - Biller J / 1998 / Guidelines for carotid endarterectomy: a statement for healthcare professionals from a Special Writing Group of the Stroke Council, American Heart Association / Circulation 97 : 501 ~ 509
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