지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.12
- 수록면
- 455 - 459 (5page)
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Purpose: The stomach is the most frequent site of gastrointestinal stromal tumor (GIST). Surgery remains the only curative treatment for GIST. Resection needs to ensure tumor free margin without lymphadenectomy. Thus partial gastric resection is the treatment of choice for gastric GIST. This study aims to review clinical characteristics between open and laparoscopic wedge resection group and evaluate safety and efficacy of laparoscopic wedge resection.
Methods: Between 1997 and 2008, 74 consecutive patients undergoing open or laparoscopic wedge resection of gastric GISTs were identified in a retrospectively collected database. Preoperative and postoperative variables were analyzed.
Results: Wedge resection with negative margin was performed in 74 patients. Laparoscopic wedge resection was performed 19 patients. Open wedge resection was performed in 55 patients. Mean tumor size of laparoscopic group was 2.7 ㎝ (range 0.4∼6.0) and open group was 4.4 cm (range 0.4∼23.0). Mean operation time of laparoscopic group was 150.0 minutes (range 80∼240), and open group was 164.6 minutes (range 75∼360). Mean hospital stay of laparoscopic group was 7.11 days (range 3∼19), and open group was 9.38 days (range 6∼20). There were no significant survival differences between groups.
Conclusion: A laparoscopic wedge resection of gastric GIST is associated with short hospitalization and not inferior to open wedge resection in terms of morbidity and mortality. The long-term outcomes between laparoscopic and open wedge resection group in our study were no significant survival differences. Long-term and prospective randomized study should be performed to confirm oncological safety of laparoscopic wedge resection.
Methods: Between 1997 and 2008, 74 consecutive patients undergoing open or laparoscopic wedge resection of gastric GISTs were identified in a retrospectively collected database. Preoperative and postoperative variables were analyzed.
Results: Wedge resection with negative margin was performed in 74 patients. Laparoscopic wedge resection was performed 19 patients. Open wedge resection was performed in 55 patients. Mean tumor size of laparoscopic group was 2.7 ㎝ (range 0.4∼6.0) and open group was 4.4 cm (range 0.4∼23.0). Mean operation time of laparoscopic group was 150.0 minutes (range 80∼240), and open group was 164.6 minutes (range 75∼360). Mean hospital stay of laparoscopic group was 7.11 days (range 3∼19), and open group was 9.38 days (range 6∼20). There were no significant survival differences between groups.
Conclusion: A laparoscopic wedge resection of gastric GIST is associated with short hospitalization and not inferior to open wedge resection in terms of morbidity and mortality. The long-term outcomes between laparoscopic and open wedge resection group in our study were no significant survival differences. Long-term and prospective randomized study should be performed to confirm oncological safety of laparoscopic wedge resection.
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REFERENCES
참고문헌 (12)
참고문헌 신청
1. [학술지(정기간행물)] - Mazur MT / 1983 / Gastric stromal tumors. Reappraisal of histogenesis / Am J Surg Pathol 7 : 507 ~ 519
2. [학술지(정기간행물)] - 석상희 / 2008 / 위와 소장에서 발생한 위장관기질종양의 예후 비교분석 - 단일기관 126예를 대상으로 한 후향적 연구 - / The Korean Journal of Pathology 42 (6) : 335 ~ 343
3. [학술지(정기간행물)] - Miettinen M / 2006 / Gastrointestinal stromal tumors: pathology and prognosis at different sites / Semin Diagn Pathol 23 : 70 ~ 83
4. [학술지(정기간행물)] - Demetri GD / 2007 / NCCN Task Force report: management of patients with gastrointestinal stromal tumor (GIST)--update of the NCCN clinical practice guidelines / J Natl Compr Canc Netw 5 : S1 ~ 29
5. [학술지(정기간행물)] - Hornick JL / 2007 / The role of KIT in the management of patients with gastrointestinal stromal tumors / Hum Pathol 38 : 679 ~ 687
2. [학술지(정기간행물)] - 석상희 / 2008 / 위와 소장에서 발생한 위장관기질종양의 예후 비교분석 - 단일기관 126예를 대상으로 한 후향적 연구 - / The Korean Journal of Pathology 42 (6) : 335 ~ 343
3. [학술지(정기간행물)] - Miettinen M / 2006 / Gastrointestinal stromal tumors: pathology and prognosis at different sites / Semin Diagn Pathol 23 : 70 ~ 83
4. [학술지(정기간행물)] - Demetri GD / 2007 / NCCN Task Force report: management of patients with gastrointestinal stromal tumor (GIST)--update of the NCCN clinical practice guidelines / J Natl Compr Canc Netw 5 : S1 ~ 29
5. [학술지(정기간행물)] - Hornick JL / 2007 / The role of KIT in the management of patients with gastrointestinal stromal tumors / Hum Pathol 38 : 679 ~ 687
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