지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.12
- 수록면
- 355 - 361 (7page)
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초록· 키워드
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We evaluated the performance of the NOW Streptococcus pneumoniae urinary antigen test, standard culture and polymerase chain reaction for detecting S. pneumoniae. The urinary antigen test of pneumonia patients represented sensitivity at 72% and specificity at 79%. The results of PCR were targeting for autolysin (lytA), pneumolysin (ply), and spn9828. The lytA sensitivity and specificity stood at 56% and 87% respectively while ply sensitivity reported 83% and specificity was 47%, sensitivity and specificity of spn9828 stood at 83% and 73% respectively. The results of urinary antigen test and three genes were all statistically meaningful within P＜0.05. When the urinary antigen test of S. pneumoniae was positive, the three kinds of genes were also likely to be positive. According to the result of urinary antigen test, the results of PCR presented a meaningful difference (P＜0.05). Especially, the urinary antigen test of S. pneumoniae was likely to be positive (P＜0.05) when more than two genes were positive in PCR results.
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REFERENCES
참고문헌 (25)
참고문헌 신청
Boersma WG / 1991 / Pneumococcal capsular antigen detection and pneumococcal serology in patients with community acquired pneumonia / Thorax 46:902~906
Bruyn GA / 1992 / Mechanisms of host defense against infection with Streptococcus pneumoniae / Clin Infect Dis 14:251~262
Burman LA / 1991 / Diagnosis of pneumonia by cultures, bacterial and viral antigen detection tests, and serology with special reference to antibodies against pneumococcal antigens / J Infect Dis 163:1087~1093
Cheong HJ / 2001 / Clinical and Genetic Characteristics of Infection by Penicillin-resistant Streptococcus pneumoniae from Community and Hospital / Korean J Infect Dis 33:112~122
Corless CE / 2001 / Simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae in suspected cases of meningitis and septicemia using real-time PCR / J Clin Microbiol 39:1553~1558
Bruyn GA / 1992 / Mechanisms of host defense against infection with Streptococcus pneumoniae / Clin Infect Dis 14:251~262
Burman LA / 1991 / Diagnosis of pneumonia by cultures, bacterial and viral antigen detection tests, and serology with special reference to antibodies against pneumococcal antigens / J Infect Dis 163:1087~1093
Cheong HJ / 2001 / Clinical and Genetic Characteristics of Infection by Penicillin-resistant Streptococcus pneumoniae from Community and Hospital / Korean J Infect Dis 33:112~122
Corless CE / 2001 / Simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae in suspected cases of meningitis and septicemia using real-time PCR / J Clin Microbiol 39:1553~1558
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UCI(KEPA) : I410-ECN-0101-2013-326-001453934