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논문 기본 정보

자료유형
학술저널
저자정보
Seong-Min Moon (동아대학교)
저널정보
대한의생명과학회 대한의생명과학회지 대한의생명과학회지 제17권 제4호
발행연도
2011.12
수록면
337 - 345 (9page)

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It is well recognized that conventional coronary artery bypass grafting (ONCAB) often leads to major organ dysfunction including renal injury. Diabetes mellitus is a major cause of nephropathy and poor clinical outcomes. The aim of this retrospective study was to evaluate the occurrence of adverse outcomes including renal impairment between diabetic (n=75, DM group) and non-diabetic patients (n=72, Non-DM group) underwent off-pump coronary artery bypass grafting surgery (OPCAB). Fasting glucose, hemoglobin A1c, fructosamine, fibrinogen and serum osmolality levels in the DM group were higher than those of the Non-DM group at pre-operative (Pre-OP) period (P<0.05). History of hypertension and renal impairment in the DM group was higher than that of the Non-DM group (P<0.05). Potassium (K?), blood urea nitrogen and creatinine levels were higher, whereas sodium (Na?) and glomerular filtration rate (GFR) levels were lower in the DM group than the Non-DM group at peri-operative period (P<0.05). Fasting glucose levels at Pre-OP period had positive correlations with blood urea nitrogen and creatinine levels at peri-operative period, but negative correlations with GFR levels at peri-operative period in the DM group (P<0.05). Incidences of renal impairment, diuretic therapy or continuous renal replacement therapy and fever in the DM group were higher than those of the Non-DM group at post-operative period (P<0.05). These results suggest that blood glucose level should be tightly controlled at peri-operative period to avoid renal dysfunction in diabetic patients.

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UCI(KEPA) : I410-ECN-0101-2013-326-001453914