With a new method of applying chitosan and alginate onto cellulose, multi-coated cotton fabrics with chitosan and alginate were prepared and characterized. To coat cotton with chitosan, raw cotton was dipped in chitosan solution, mangled of 1kgf/㎠, neutralized in 2 wt% NaOH soluton, washed, and dried at 60℃ oven. The chitosan-coated fiber was dipped in sodium alginate solution, 1kgf/㎠ mangled, neutralized in 2 wt% CaCl<SUB>2</SUB> solution, washed, and dried at 60℃ oven, resulting in CCAC(coated cotton with chitosan and calcium alginate skin) fiber characteristics. Excellent absorbancy of distilled water and saline solution was observed by the absorption test on cotton fabric treated with CCAC(0.5 wt% calcium alginate) and 0.5 wt% calcium alginate respectively. The SEM photograph confirmed the uniform coating on the cotton fabric surface.