지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.12
- 수록면
- 231 - 240 (10page)
이용수
초록· 키워드
오류제보하기
Gryllus bimaculatus (Gb) was orally administered at doses of 0, 0.04, 0.2, 1 and 5 g/kg bw/day for 13 consecutive weeks. There were no observed clinical signs or deaths related to treatment in all the groups tested. Therefore, the approximate lethal oral dose of G. bimaculatus was considered to be higher than 5 g/ kg in rats. Throughout the administration period, no significant changes in diet consumption, ophthalmologic findings, organ weight, clinical pathology (hematology, clinical chemistry, coagulation, and urinalysis) or gross pathology were detected. Minor changes were found in hematological parameters for the 5 g/kg Gb-treated group (triglyceride reduction of 35.8%), but all changes were within normal physiological ranges. Microscopic examination did not identify any treatment-related histopathologic changes in the organs of Gb-treated rats in the high dose group. From these results, one can conclude that the no-observed adverse effect level (NOAEL) of G. bimaculatus is higher than 5 g/kg bw/day in rats.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENT
REFERENCES
참고문헌 (9)
참고문헌 신청
Ahn, M.Y. / 2000 / Effects of cricket supplements on the chickenmeats and its eggs / Korean J. Poult. Sci 27:169~282
안미영 / 2002 / 귀뚜라미의 수용성 및 알코올 추출물의 간보호효과 / 한국식품과학회지 34(4):684~687
안미영 / 2004 / 귀뚜라미의 물 및 메탄올 추출물이 알코올 대사에 미치는 효과 / 생약학회지 35(2):175~178
Ahn, M.Y. / 2005 / Genotoxic evaluation of the biocomponents of thecricket, Gryllus bimaculatus, using three mutagenicity tests / J.Toxicol. Environ. Health A 68:2111~2118
Cui, Z. / 2002 / Materia medicafrom insects :137~145
안미영 / 2002 / 귀뚜라미의 수용성 및 알코올 추출물의 간보호효과 / 한국식품과학회지 34(4):684~687
안미영 / 2004 / 귀뚜라미의 물 및 메탄올 추출물이 알코올 대사에 미치는 효과 / 생약학회지 35(2):175~178
Ahn, M.Y. / 2005 / Genotoxic evaluation of the biocomponents of thecricket, Gryllus bimaculatus, using three mutagenicity tests / J.Toxicol. Environ. Health A 68:2111~2118
Cui, Z. / 2002 / Materia medicafrom insects :137~145
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UCI(KEPA) : I410-ECN-0101-2013-513-001112900