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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.12
- 수록면
- 1,185 - 1,190 (6page)
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초록· 키워드
오류제보하기
When 10 kinds of herbal medicines were fractionated into hexane, MeOH, cold-water, and hot-water extracts, hotwater extracts from Acanthopanax senticosus (AS), Glycyrrhiza uralensis (GU), Cichorium intybus (CI), and Polygonatum odoratum (PO) showed the potent intestinal immune system modulating activity (1.72-, 1.62-, 1.60-, and 1.53-fold of control at 100 ㎍/㎖, respectively). Especially, hot-water extracts from AS (215% compared with the control) and GU (187%) also had macrophages stimulating activity and mitogenic activity of splenocytes (7.1- and 6.5-fold) at 100 ㎍/㎖. In addition, the effects of hot-water extracts from herbal medicines on anticancer activities were studied in mice. Hot-water extracts from AS and GU enhanced cytotoxicity of natural killer cell against cancer cell, Yac-1 (37 and 34% cytotoxicity) at E/T ratio 100:1, and colon 26-M3.1 cancer cell lines had significantly inhibited (82.1 and 75.2%) in experimental lung metastasis. These results suggest that hot-water extracts from A. senticosus and G. uralensis can be used as biological response modifiers to stimulate immune system and inhibit tumor.
목차
Abstract
Introduction
Materials and Methods
Results and Discussion
Acknowledgments
References
참고문헌 (33)
참고문헌 신청
Lemberkovics É / 2002 / Comparative evaluation of Helichrysi flos herbal extracts as dietary sources of plant polyphenols, and macro- and microelements / Food Chem 78:119~127
Akramiene D / 2007 / Effects of beta-glucans on the immune system / Medicina 43:597~606
Tang W / 2003 / Recent development of antitumor agents from Chinese herbal medicines. Part II. High molecular compounds (3) / Planta Med 69:193~201
Davydov M / 2000 / Eleutherococcus senticosus (Rupr. & Maxim) Maxim. (Araliaceae) as an adaptogen: A closer look / J. Ethnopharmacol 72:345~393
Sook-Jeong Shin / 2005 / Acanthopanax and Platycodi Independently Prevents the Onset of HighFat Diet Induced Hyperglyceridemia and Obesity in C57BL/6 Mice / Food Science and Biotechnology 14(6):841~846
Akramiene D / 2007 / Effects of beta-glucans on the immune system / Medicina 43:597~606
Tang W / 2003 / Recent development of antitumor agents from Chinese herbal medicines. Part II. High molecular compounds (3) / Planta Med 69:193~201
Davydov M / 2000 / Eleutherococcus senticosus (Rupr. & Maxim) Maxim. (Araliaceae) as an adaptogen: A closer look / J. Ethnopharmacol 72:345~393
Sook-Jeong Shin / 2005 / Acanthopanax and Platycodi Independently Prevents the Onset of HighFat Diet Induced Hyperglyceridemia and Obesity in C57BL/6 Mice / Food Science and Biotechnology 14(6):841~846
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UCI(KEPA) : I410-ECN-0101-2013-573-000858327