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논문 기본 정보

자료유형
학술저널
저자정보
Suk-Yul Jung (Namseoul University)
저널정보
대한의생명과학회 대한의생명과학회지 대한의생명과학회지 제17권 제3호
발행연도
2011.9
수록면
173 - 176 (4page)

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초록· 키워드

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Free-living Acanthamoeba are eukaryotic protozoan organisms that are widely distributed in the air, water, etc such as environment. Acanthamoeba ingest the Escherichia coli which will replicate in cytoplasm of Acanthamoeba. Bacterial pathogenicity or virulence is one of important determinant factors to survive in free-living Acanthamoeba and otherwise Acanthamoebic pathogenicity is also an important factor for their interactions. Bacterial association with pathogenic strain of Acanthamoeba T1 and T4 was lower about two times than non-pathogenic T7. Bacterial invasion percentages into T1 were higher about three times than T7 but bacterial survival in T7 was increased as T1. The capsule-deletion mutant exhibited limited ability for invasion/uptake by and survival inside pathogenic Acanthamoeba T4. E. coli-outer membrane protein A (OmpA) decreased bacterial association with A. castellanii by about three times and it had higher effects than lipopolysaccharides (LPS). Under favorable conditions, the mutants were not survived in Acanthamoeba up to 24 h incubation. Therefore, this review will report pathogenic and non-pathogenic Acanthamoeba strains interactions with E. coli and its several mutants, i.e., capsule, OmpA and LPS.

목차

Acanthamoeba encephalitis, keratitis and taxonomy
Interaction of Acanthamoeba and Escherichia coli K1
Bacteria mutants interactions with Acanthamoeba
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