지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.9
- 수록면
- 148 - 151 (4page)
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초록· 키워드
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We describe here a multicentric spontaneous malignant schwannoma obtained from one male F344 rat, and this animal was the subject of a carcinogenicity study for which it was treated with diisodecyl phthalate. The animal of the control group not treated with diisodecyl phthalate showed dyspnea and severe lordosis. On the necropsy, two tan, firm, encapsulated masses were observed in the subcutis of the lumbosacral region and the left inguinal region of the abdominal cavity, respectively; the masses were 25 × 17 × 8 ㎜ and 16 × 14 × 8 ㎜ in size, respectively. Histologically, the tumor consisted of spindle and pleomorphic cells that grew in various patterns, that was, sweeping fascicles and herringbone and local organoid patterns. The pleomorphic neoplastic cells had more than two nuclei. Additionally, the diagnosis of malignant schwannoma was confirmed by the immune reactivity of the tumor cells for S-100 protein.
목차
INTRODUCTION
MATERIALS AND METRHODS
RESULTS AND DISCUSSION
ACKNOWLEDGEMENT
REFERENCES
참고문헌 (14)
참고문헌 신청
Cho, W.S. / 2008 / Peroxisome proliferatordi-isodecyl phthalate has no carcinogenic potential in Fischer344 rats / Toxicol. Lett 178:110~116
Colmenero, C. / 1991 / Maxillofacial malignant peripheral nerve sheath tumours / J. Craniomaxillofac. Surg 19:40~46
Giangaspero, F. / 1989 / Malignant peripheral nerve sheath tumors and spindlecell sarcomas: an immunohistochemical analysis of multiplemarkers / Appl. Pathol 7:134~144
Gray, M.H. / 1989 / Glial fibrillary acidic protein and keratin expression bybenign and malignant nerve sheath tumors / Hum. Pathol 20:1089~1096
Goodman, D.G. / 1979 / Neoplastic and nonneoplastic lesions in agingF344 rats / Toxicol. Appl. Pharmacol 48:237~248
Colmenero, C. / 1991 / Maxillofacial malignant peripheral nerve sheath tumours / J. Craniomaxillofac. Surg 19:40~46
Giangaspero, F. / 1989 / Malignant peripheral nerve sheath tumors and spindlecell sarcomas: an immunohistochemical analysis of multiplemarkers / Appl. Pathol 7:134~144
Gray, M.H. / 1989 / Glial fibrillary acidic protein and keratin expression bybenign and malignant nerve sheath tumors / Hum. Pathol 20:1089~1096
Goodman, D.G. / 1979 / Neoplastic and nonneoplastic lesions in agingF344 rats / Toxicol. Appl. Pharmacol 48:237~248
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UCI(KEPA) : I410-ECN-0101-2013-513-000310502