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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.3
- 수록면
- 7 - 13 (7page)
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초록· 키워드
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Objectives: N-Nitrosodimethylamine (NDMA) is classified as a probable human carcinogen by the United States Environmental Protection Agency (US EPA) and is formed during the chlorination of municipal drinking water. In this study, selected nitrosamines were measured in chlorinated drinking water collected from Chuncheon, Kangwon-do, Republic of Korea, and a risk assessment for NDMA was conducted.
Methods: Twelve water samples were collected from 2 treatment plants and 10 household taps. Samples were analyzed for 6 nitrosamines via solid-phase extraction cleanup followed by conversion to dansyl derivatives and high-performance liquid chromatography-fluorescence detection (HPLC-FLD). Considering the dietary patterns of Korean people and the concentration change of NDMA by boiling, a carcinogenic risk assessment from ingestion exposure was conducted following the US EPA guidelines.
Results: NDMA concentrations ranged between 26.1 and 112.0 ng/ℓ. NDMA in water was found to be thermally stable, and thus its concentration at the end of boiling was greater than before thermal treatment owing to the decrease in water volume. The estimated excess lifetime carcinogenic risk exceeded the regulatory baseline risk of 10-5.
Conclusions: This result suggests that more extensive studies need to be conducted on nitrosamine concentration distributions over the country and the source of relatively high nitrosamine concentrations.
Methods: Twelve water samples were collected from 2 treatment plants and 10 household taps. Samples were analyzed for 6 nitrosamines via solid-phase extraction cleanup followed by conversion to dansyl derivatives and high-performance liquid chromatography-fluorescence detection (HPLC-FLD). Considering the dietary patterns of Korean people and the concentration change of NDMA by boiling, a carcinogenic risk assessment from ingestion exposure was conducted following the US EPA guidelines.
Results: NDMA concentrations ranged between 26.1 and 112.0 ng/ℓ. NDMA in water was found to be thermally stable, and thus its concentration at the end of boiling was greater than before thermal treatment owing to the decrease in water volume. The estimated excess lifetime carcinogenic risk exceeded the regulatory baseline risk of 10-5.
Conclusions: This result suggests that more extensive studies need to be conducted on nitrosamine concentration distributions over the country and the source of relatively high nitrosamine concentrations.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
CONCLUSIONS
ACKNOWLEDGEMENTS
CONFLICT OF INTEREST
REFERENCES
참고문헌 (24)
참고문헌 신청
1. [학술지(정기간행물)] - Mitch WA / 2003 / N-Nitrosodimethylamine (NDMA) as a drinking water contaminant: a review / Environ Eng Sci 20 (5) : 389 ~ 404
2. [인터넷자원] - California Department of Health / / A brief history of NDMA findings in drinking water
3. [학술지(정기간행물)] - Firstachi A / 2007 / Estimation of the total daily oral intake of NDMA attributable to drinking water / J Water Health 5 (3) : 341 ~ 355
4. [인터넷자원] - Dillon G / / NDMA - concentrations in drinking water and factors affecting its formation (CSA7240 / WT02049 / DWI 70/2/210)
5. [학술지(정기간행물)] - Plumlee MH / 2008 / N-nitrosodimethylamine (NDMA) removal by reverse osmosis and UV treatment and analysis via LC-MS/MS / Water Res 42 (1) : 347 ~ 355
2. [인터넷자원] - California Department of Health / / A brief history of NDMA findings in drinking water
3. [학술지(정기간행물)] - Firstachi A / 2007 / Estimation of the total daily oral intake of NDMA attributable to drinking water / J Water Health 5 (3) : 341 ~ 355
4. [인터넷자원] - Dillon G / / NDMA - concentrations in drinking water and factors affecting its formation (CSA7240 / WT02049 / DWI 70/2/210)
5. [학술지(정기간행물)] - Plumlee MH / 2008 / N-nitrosodimethylamine (NDMA) removal by reverse osmosis and UV treatment and analysis via LC-MS/MS / Water Res 42 (1) : 347 ~ 355
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UCI(KEPA) : I410-ECN-0101-2012-539-004472298