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논문 기본 정보

자료유형
학술저널
저자정보
Jeung Hee Lee (충남대학교) Chan Wook Son (충남대학교) Mi Yeon Kim (충남대학교) Min Hee Kim (충남대학교) Hye Ran Kim (충남대학교) Eun Shil Kwak (충남대학교) Sena Kim (농촌진흥청) Mee Ree Kim (충남대학교)
저널정보
한국영양학회 Nutrition Research and Practice Nutrition Research and Practice Vol.3 No.2
발행연도
2009.6
수록면
114 - 121 (8page)

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The effect of diet supplemented with red beet (Beta vulgaris L.) leaf on antioxidant status of plasma and tissue was investigated in C57BL/6J mice. The mice were randomly divided into two groups after one-week acclimation, and fed a high fat (20%) and high cholesterol (1%) diet without (control group) or with 8% freeze-dried red beet leaf (RBL group) for 4 weeks. In RBL mice, lipid peroxidation determined as 2-thiobarbituric acid-reactive substances (TBARS value) was significantly reduced in the plasma and selected organs (liver, heart, and kidney). Levels of antioxidants (glutathione and β-carotene) and the activities of antioxidant enzyme (glutathione peroxidase) in plasma and liver were considerably increased, suggesting that antioxidant defenses were improved by RBL diet. Comet parameters such as tail DNA (%), tail extent moment, olive tail moment and tail length were significantly reduced by 25.1%, 49.4%, 35.4%, and 23.7%, respectively, in plasma lymphocyte DNA of RBL mice compared with control mice, and indicated the increased resistance of lymphocyte DNA to oxidative damage. In addition, the RBL diet controlled body weight together with a significant reduction of fat pad (retroperitoneal, epididymal, inguinal fat, and total fat). Therefore, the present study suggested that the supplementation of 8% red beet leaf in high fat high cholesterol diet could prevent lipid peroxidation and improve antioxidant defense system in the plasma and tissue of C57BL/6J mice.

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Abstract
Introduction
Materials and Methods
Results
Discussion
Literature cited

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UCI(KEPA) : I410-ECN-0101-2012-594-004464379