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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
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This study was conducted to investigate the effects of 8 weeks deep-sea water supplementation and swimming exercise on lipid metabolism and antioxidant enzymes of rats. Thirty-two SD male rats, 6 weeks of age, were randomly divided into 4 groups: (HS : high fat diet sedentary group n=8); (HE: high fat diet exercised group n=8); (DS: deep-sea water supplemented sedentary group n=8); (DE : deep-sea water supplemented exercised group n=8), given a high fat diet and free access to tap water (HS and HE) or deep-sea water (DS and DE) for 8 weeks, and housed in groups of two per cage under controlled temperature(23±1℃) and relative humidity(50±5%). The light/dark cycle was automatically controlled(alternation 12-h periods) and lighting was begun at 8:00. The animals in the swim groups swam for 60 min/day-1, 5 days/wk, 2% load/weight for 8weeks in a large plastic tube filled with water(temp. : 35±1℃, depth : 50㎝, radius : 25㎝). In the results, Serum TG level of DS group was lower than HS group, but there was no significantly difference. Furthermore, PPAR-γ and PGC-1α were slightly increased in deep-sea water supplemented groups. The Mn-SOD protein expression of DS group was significantly higher than HS group (p＜.01) and the value of DE was slightly higher than HE group. These results suggest that deep-sea water supplementation and exercise has a positive effect on lipid metabolism and antioxidant enzymes in rats by decreasing serum TG levels, and increasing PPAR-γ, PGC-1α, and Mn-SOD protein expression.
목차
Abstract
Ⅰ. 서론
Ⅱ. 연구방법
Ⅲ. 결과
Ⅳ. 논의
참고문헌
참고문헌 (44)
참고문헌 신청
1. [학술지(정기간행물)] - 조중석 / 2006 / 지구성 트레이닝에 따른 흰쥐 골격근내 PPAR-α, PPAR-γ 및 PGC-1α Protein의 발현 / Journal of Exercise Nutrition & Biochemistry 10 (3) : 289 ~ 296
2. [학술지(정기간행물)] - Akpinar, D. / 2008 / The effect of lipoic acid on antioxidant status and lipid peroxidation in rats exposed to chronic restraint stress / Physiol Res 57 : 893 ~ 901
3. [학술지(정기간행물)] - Baar, K. / 2002 / Adaptations of skeletal muscle to exericse: rapid increase in the transcriptional coactivator PGC-1 / FASEB J 16 : 1879 ~ 1886
4. [학술지(정기간행물)] - Cresci, S. / 1996 / Activation of a novel metabolic gene regulatory pathway by chronic stimulation of skeletal muscle / Am J Physiol 270 : 413 ~ 420
5. [학술지(정기간행물)] - Desvergne, B. / 1999 / Peroxisome proliferator-activated receptors: nuclear control of metabolism / Endocr Rev 20 : 649 ~ 688
2. [학술지(정기간행물)] - Akpinar, D. / 2008 / The effect of lipoic acid on antioxidant status and lipid peroxidation in rats exposed to chronic restraint stress / Physiol Res 57 : 893 ~ 901
3. [학술지(정기간행물)] - Baar, K. / 2002 / Adaptations of skeletal muscle to exericse: rapid increase in the transcriptional coactivator PGC-1 / FASEB J 16 : 1879 ~ 1886
4. [학술지(정기간행물)] - Cresci, S. / 1996 / Activation of a novel metabolic gene regulatory pathway by chronic stimulation of skeletal muscle / Am J Physiol 270 : 413 ~ 420
5. [학술지(정기간행물)] - Desvergne, B. / 1999 / Peroxisome proliferator-activated receptors: nuclear control of metabolism / Endocr Rev 20 : 649 ~ 688
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UCI(KEPA) : I410-ECN-0101-2012-692-004178497