지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.9
- 수록면
- 249 - 255 (7page)
이용수
초록· 키워드
오류제보하기
In order to assess the microbiological contamination of laboratory mice and rats in Korea over the 2-year period from 2007 to 2008, we monitored animals housed in mouse and rat facilities equipped with barrier systems. In a barrier animal facility in Korea, the most important viruses in the identified pathogen were the mouse hepatitis virus (MHV) and Pasteurella (Pa.) pneumotropica, and Staphylococcus aureus was identified as the most common bacterial pathogen in Korea. The most commonly detected parasite in the identified pathogen was Trichomonas spp. in the mouse facilities and Entamoeba spp. in the rat facilities. In many cases, these pathogen-contaminated animals were genetically modified animals obtained from the university. Currently, consistent with the increased transfer of genetically modified animals between domestic and foreign animal facilities, the Pa. pneumotropica and parasites infection rates were shown to have increased as compared to those of the 2004-2006 period. Indeed, the MHV infection rate has been maintained at almost 20% in Korean animal facilities over the past 10 years. These results showed that effective quarantine programs for contaminated genetically engineered mutant mice and the monitoring of regular or irregular MHV monitoring in animal colonies should help to reduce pathogen contamination in Korean animal facilities.
목차
재료 및 방법
결과
고찰
감사의 글
참고문헌
참고문헌 (16)
참고문헌 신청
1. [학술지(정기간행물)] - Baker, D.G. / 1998 / Natural pathogens of laboratory mice, rats, and rabbits and their effects on research / Clin. Microbiol. Rev. 11 : 231 ~ 266
2. [학술지(정기간행물)] - Fox, J.G. / 1997 / The role of Helicobacter species in newly recognized gastrointestinal tract diseases of animals / Lab. Anim. Sci. 47 : 222 ~ 255
3. [학술지(정기간행물)] - Fox, J.G. / 1994 / Helicobacter hepaticus sp. nov., a microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice / J. Clin. Microbiol. 32 : 1238 ~ 1245
4. [학술지(정기간행물)] - Hayashimoto, N. / 2005 / Identification procedure for Pasteurella pneumotropica in microbiologic monitoring of laboratory animals / Exp. Anim. 54 : 123 ~ 129
5. [학술지(정기간행물)] - Hsu, C.C. / 2005 / Development of a microsphere-based serologic multiplexed fluorescent immunoassay and a reverse transcriptase PCR assay to detect murine norovirus 1 infection in mice / Clin. Diagn. Lab. Immunol. 12 : 1145 ~ 1151
2. [학술지(정기간행물)] - Fox, J.G. / 1997 / The role of Helicobacter species in newly recognized gastrointestinal tract diseases of animals / Lab. Anim. Sci. 47 : 222 ~ 255
3. [학술지(정기간행물)] - Fox, J.G. / 1994 / Helicobacter hepaticus sp. nov., a microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice / J. Clin. Microbiol. 32 : 1238 ~ 1245
4. [학술지(정기간행물)] - Hayashimoto, N. / 2005 / Identification procedure for Pasteurella pneumotropica in microbiologic monitoring of laboratory animals / Exp. Anim. 54 : 123 ~ 129
5. [학술지(정기간행물)] - Hsu, C.C. / 2005 / Development of a microsphere-based serologic multiplexed fluorescent immunoassay and a reverse transcriptase PCR assay to detect murine norovirus 1 infection in mice / Clin. Diagn. Lab. Immunol. 12 : 1145 ~ 1151
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UCI(KEPA) : I410-ECN-0101-2012-510-003686433