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논문 기본 정보

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학술저널
저자정보
Wi-Han Kim (경북대학교) Chan-Il Kim (경북대학교) Sang-Won Lee (경북대학교) Soo-Hee Lim (경북대학교) Cheol-Woo Park (경북대학교) Ho Lee (경북대학교) Min-Kyu Park (영남이공대학)
저널정보
한국광학회 Current Optics and Photonics Journal of the Optical Society of Korea Vol.14 No.1
발행연도
2010.3
수록면
42 - 48 (7page)

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초록· 키워드

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We used video-rate Confocal Laser Scanning Microscopy (CLSM) to observe the motion of blood cells in a micro-channel. Video-rate CLSM allowed us to acquire images at the rate of 30 frames per second. The acquired images were used to perform Particle Image Velocimetry (PIV), thus providing the velocity profile of the blood in a micro-channel. While previous confocal microscopy-assisted PIV required exogenous micro/nano particles as the tracing particles, we employed blood cells as tracing particles for the CLSM in the reflection mode, which uses light back-scattered from the sample. The blood flow at various depths of the micro-channel was observed by adjusting the image plane of the microscope. The velocity profile at different depths of the channel was measured. The confocal micro-PIV technique used in the study was able to measure blood velocity up to a few hundreds μm/sec, equivalent to the blood velocity in the capillaries of a live animal. It is expected that the technique presented can be applied for in vivo blood flow measurement in the capillaries of live animals.

목차

Ⅰ. INTRODUCTION
Ⅱ. METHODOLOGY
Ⅲ. EXPERIMENTAL RESULTS
Ⅳ. DISCUSSION AND CONCLUSION
ACKNOWLEDGMENT
REFERENCES

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UCI(KEPA) : I410-ECN-0101-2010-425-002173408