지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.12
- 수록면
- 190 - 198 (9page)
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Objectives: Decreased bone mineral density(BMD) in patients with schizophrenia on anti psychotics has been attributed to a variety of factors such as hyperprolactinemia, low levels physical activities, decreased calcium intake, reduced exposure to sunlight. In this study, we examined the correlation between risk factors causes of decreased BMD in patients with schizophrenia.
Methods: We screened 22 patients with schizophrenia who treated with antipsychotics for at least one year. We estimated serum prolactin, sexual hormones, biological markers of bone turnover, epidemiologic factors influencing decreased BMD. And we also examined the correlation of positive and negative syndrome scale(PANSS), lumbar spine and femoral neck BMD.
Results: The study subjects have hyperprolactinemia. Among them, 3 subjects showed osteoporosis and 3 subjects showed osteopenia. BMD showed a negative correlation with hallucinatory behavior, emotional withdrawal, passive/apathetic social withdrawal, lack of spontaneity and flow of conversation, disturbance of volition of PANSS and BMI. BMD showed no correlation with serum prolactin, other risk factors of decreased BMD.
Conclusion: Decreased BMD observed in patients with schizophrenia correlated with psychopathology of schizophrenia.
Methods: We screened 22 patients with schizophrenia who treated with antipsychotics for at least one year. We estimated serum prolactin, sexual hormones, biological markers of bone turnover, epidemiologic factors influencing decreased BMD. And we also examined the correlation of positive and negative syndrome scale(PANSS), lumbar spine and femoral neck BMD.
Results: The study subjects have hyperprolactinemia. Among them, 3 subjects showed osteoporosis and 3 subjects showed osteopenia. BMD showed a negative correlation with hallucinatory behavior, emotional withdrawal, passive/apathetic social withdrawal, lack of spontaneity and flow of conversation, disturbance of volition of PANSS and BMI. BMD showed no correlation with serum prolactin, other risk factors of decreased BMD.
Conclusion: Decreased BMD observed in patients with schizophrenia correlated with psychopathology of schizophrenia.
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UCI(KEPA) : I410-ECN-0101-2010-513-001908208